砷转运蛋白家族。
Families of arsenic transporters.
作者信息
Rosen B P
机构信息
Dept of Biochemistry and Molecular Biology, Wayne State University, School of Medicine, Detroit, MI 48201, USA.
出版信息
Trends Microbiol. 1999 May;7(5):207-12. doi: 10.1016/s0966-842x(99)01494-8.
Abstract
Bacterial arsenic resistance (ars) operons encode an arsenite-efflux system that can be a secondary carrier protein (ArsB) or an anion-translocating ATPase (ArsAB). Yeasts extrude arsenite using Acr3p, a plasma membrane carrier protein, or sequester it in vacuoles as the glutathione conjugate using Ycf1p, an ABC transporter.
摘要
细菌抗砷（ars）操纵子编码一种亚砷酸盐外排系统，该系统可以是一种次级载体蛋白（ArsB）或一种阴离子转运ATP酶（ArsAB）。酵母通过质膜载体蛋白Acr3p排出亚砷酸盐，或者通过ABC转运蛋白Ycf1p将其作为谷胱甘肽共轭物隔离在液泡中。
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