用麻风分枝杆菌纯蛋白衍生物进行的迟发型超敏反应试验。
Delayed hypersensitivity tests with Mycobacterium leprae purified protein derivative.
作者信息
Bedi B M, Harris E B, Narayanan E, Kirchheimer W F
出版信息
Lepr India. 1976 Jan;48(1):8-18.
Skin tests were conducted on 3 lepromatous, 3 dimorphous and 6 tuberculoid leprosy patients and 3 others not suffering from leprosy with lepromin, purified protein derivative from M. leprae of armadillo origin and tuberculin. Results show that a delayed hypersensitivity reaction could be produced with PPD in 72 hours on all Mitsuda positive cases, with one anomalous exception, without cross reaction to tuberculin. The results were promising from the point of view of substituting lepromin with PPD in usual tests.
对3例瘤型、3例界线类和6例结核样型麻风患者以及3例非麻风患者进行了麻风菌素、犰狳源麻风杆菌纯化蛋白衍生物和结核菌素的皮肤试验。结果显示，除1例异常情况外，所有麻风菌素阳性病例在72小时内对纯化蛋白衍生物均产生了迟发型超敏反应，且与结核菌素无交叉反应。从在常规试验中用纯化蛋白衍生物替代麻风菌素的角度来看，结果很有前景。
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