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通过对一名截瘫患者进行前列腺按摩获取精子,经卵胞浆内单精子注射实现三胎妊娠:病例报告

Triplet pregnancy achieved through intracytoplasmic sperm injection with spermatozoa obtained by prostatic massage of a paraplegic patient: case report.

作者信息

Marina S, Marina F, Alcolea R, Nadal J, Pons M C, Grossmann M, Expósito R, Vidal J

机构信息

Instituto de Reproducción CEFER (Centro Médico Teknon), Marquesa de Vilallonga, 08017 Barcelona, Spain.

出版信息

Hum Reprod. 1999 Jun;14(6):1546-8. doi: 10.1093/humrep/14.6.1546.

Abstract

Spinal cord-injured men with ejaculation disorders can have children thanks to assisted reproduction techniques. Spermatozoa from these patients are usually obtained through vibratory stimulation, electroejaculation or by puncturing the seminal duct or the testicle. We present the first published case, as far as we are aware, of spermatozoa obtained through prostatic massage of a paraplegic patient. Penile vibratory stimulation was unsuccessful in this patient. In-vitro fertilization (IVF) with intracytoplasmic sperm injection (ICSI) with spermatozoa obtained through electroejaculation was performed at another centre but pregnancy was not achieved. Through prostatic massage, we obtained a total semen volume of 6 ml containing a total count of 12.32x10(6) spermatozoa (6.24x10(6) with tails), 8% of which had motility (graded + and ++); and 16% of which had normal morphology. The spermatozoa obtained were then used to perform IVF with ICSI and a triplet pregnancy was achieved. Prostatic massage appears to be an easy, non-traumatic and risk-free method to obtain spermatozoa from paraplegic patients.

摘要

借助辅助生殖技术,患有射精障碍的脊髓损伤男性能够生育子女。这些患者的精子通常通过振动刺激、电射精或穿刺输精管或睾丸获取。据我们所知,我们报告了首例通过对截瘫患者进行前列腺按摩获取精子的病例。该患者阴茎振动刺激未成功。另一个中心对通过电射精获取的精子进行了卵胞浆内单精子注射(ICSI)的体外受精(IVF),但未实现妊娠。通过前列腺按摩,我们获得了总量为6毫升的精液,其中精子总数为12.32×10⁶(有尾精子6.24×10⁶),其中8%具有活力(分级为+和++);16%形态正常。然后将获取的精子用于进行ICSI的IVF,并实现了三胎妊娠。前列腺按摩似乎是一种从截瘫患者获取精子的简便、无创且无风险的方法。

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