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脊髓损伤所致不射精患者的逆行输精管精子抽吸术

Retrograde vasal sperm aspiration in anejaculatory patients with spinal cord injury.

作者信息

Hibi Hatsuki, Ohori Tadashi, Yamada Yoshiaki, Honda Nobuaki, Hashiba Yoshiki, Asada Yoshimasa

机构信息

Department of Urology, Kyoritsu General Hospital, Nagoya.

Department of Urology, Aichi Medical University, Nagakute, and.

出版信息

Reprod Med Biol. 2008 Aug 3;7(3):115-118. doi: 10.1111/j.1447-0578.2008.00207.x. eCollection 2008 Sep.

DOI:10.1111/j.1447-0578.2008.00207.x
PMID:29699291
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5904623/
Abstract

This paper describes our experience with retrograde vasal sperm aspiration (ReVSA) in anejaculatory patients with spinal cord injury. We performed 11 vasal sperm aspiration procedures on eight patients presenting with neurogenic anejaculation associated with spinal cord injury at our institute between 2004 and 2007. This procedure was conducted under local anesthesia with a spermatic block. A 24G needle was inserted into the vas in a retrograde fashion. Sperm-washing medium was gently injected into the proximal vas several times and collected. Aspirated sperm was cryopreserved for intracytoplasmic sperm injection. Adequate motile sperm was obtained from all patients. All couples underwent intracytoplasmic sperm injection; clinical pregnancies were achieved in eight cases (two ongoing pregnancies and the births of six healthy babies). Retrograde vasal sperm aspiration is a reliable method for the consistent recovery of sperm of sufficient quality to afford a high pregnancy rate and in sufficient quantity to permit cryopreservation of excess sperm for future use. (Reprod Med Biol 2008; : 115-118).

摘要

本文描述了我们对脊髓损伤所致不射精患者进行逆行输精管精子抽吸术(ReVSA)的经验。2004年至2007年期间,我们在本研究所对8例因脊髓损伤导致神经源性不射精的患者进行了11次输精管精子抽吸手术。该手术在局部麻醉加精索阻滞下进行。用24G针头以逆行方式插入输精管。将精子洗涤介质轻轻注入输精管近端几次并收集。抽吸的精子冷冻保存用于卵胞浆内单精子注射。所有患者均获得了足够数量的活动精子。所有夫妇均接受了卵胞浆内单精子注射;8例临床妊娠成功(2例正在妊娠,6例诞下健康婴儿)。逆行输精管精子抽吸术是一种可靠的方法,能够持续获取质量足够高、数量足够多的精子,以实现高妊娠率,并能保存多余精子用于冷冻以备将来使用。(《生殖医学与生物学》2008年;:115 - 118)

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本文引用的文献

1
Comparison of three sperm retrieval techniques in spinal cord-injured men: pregnancy outcome.脊髓损伤男性三种取精技术的比较:妊娠结局
Gynecol Endocrinol. 2006 May;22(5):252-5. doi: 10.1080/09513590600647326.
2
Male infertility: evaluation and sperm retrieval.男性不育症:评估与精子获取
Clin Obstet Gynecol. 2006 Mar;49(1):55-72. doi: 10.1097/01.grf.0000197267.02541.ae.
3
[Clinical results of infertility treatment to male patients with spinal cord injury].[脊髓损伤男性患者不育治疗的临床结果]
Hinyokika Kiyo. 2004 Jan;50(1):21-3.
4
Acute management of autonomic dysreflexia: individuals with spinal cord injury presenting to health-care facilities.自主神经反射异常的急性处理:脊髓损伤患者前往医疗机构就诊的情况。
J Spinal Cord Med. 2002 Spring;25 Suppl 1:S67-88.
5
Ampullary, seminal vesicular, and prostatic massage for obtaining spermatozoa from patients with anejaculation.壶腹、精囊和前列腺按摩以从射精不能患者获取精子
Fertil Steril. 2001 Jun;75(6):1236-7. doi: 10.1016/s0015-0282(01)01785-x.
6
Sperm motility from the vas deferens of spinal cord injured men is higher than from the ejaculate.脊髓损伤男性输精管中的精子活力高于射精中的精子活力。
J Urol. 2000 Sep;164(3 Pt 1):712-5. doi: 10.1097/00005392-200009010-00022.
7
Vigorous prostatic massage: a simple method to retrieve spermatozoa for intracytoplasmic sperm injection in psychogenic anejaculation: case report.
Hum Reprod. 1999 Aug;14(8):2050-3. doi: 10.1093/humrep/14.8.2050.
8
A comprehensive approach to the management of male infertility following spinal cord injury.脊髓损伤后男性不育症管理的综合方法。
Spinal Cord. 1999 Jul;37(7):508-14. doi: 10.1038/sj.sc.3100866.
9
Triplet pregnancy achieved through intracytoplasmic sperm injection with spermatozoa obtained by prostatic massage of a paraplegic patient: case report.通过对一名截瘫患者进行前列腺按摩获取精子,经卵胞浆内单精子注射实现三胎妊娠:病例报告
Hum Reprod. 1999 Jun;14(6):1546-8. doi: 10.1093/humrep/14.6.1546.
10
Assisted fertility using electroejaculation in men with spinal cord injury--a review of literature.脊髓损伤男性使用电射精辅助生育——文献综述
Fertil Steril. 1995 Jul;64(1):1-9.