Avakian R M, Dutov A A, Tolpyshev B A
Farmakol Toksikol. 1976 Nov-Dec;39(6):647-51.
In chronic experiments with freely moving cats the action of diverse metrazol doses on the d,1-amphetamine-induced stereotype behaviour and the arrest reaction following low frequency stimulation of the caudate nucleus was studied. After injections of metrazol (20--30 mg/kg, i.c.) myoclonic seizure jerks and decreased locomotion occurred. This state was accompanied by depression of the stereotype behaviour and lowered arrest reaction threshold. It is suggested that some behavioural and the EEG metrazol-induced changes may come as a result of the caudate nucleus activation.
在对自由活动的猫进行的慢性实验中,研究了不同剂量的戊四氮对d,l-苯丙胺引起的刻板行为以及尾状核低频刺激后的制止反应的作用。注射戊四氮(20 - 30毫克/千克,腹腔注射)后,出现肌阵挛性惊厥抽搐和运动减少。这种状态伴随着刻板行为的抑制和制止反应阈值的降低。有人认为,戊四氮引起的一些行为和脑电图变化可能是尾状核激活的结果。