Raymer A M, Merians A S, Adair J C, Schwartz R L, Williamson D J, Rothi L J, Poizner H, Heilman K M
Dept. of ESSE, Old Dominion University, Norfolk, VA 23529-0136, USA.
Cortex. 1999 Apr;35(2):183-99. doi: 10.1016/s0010-9452(08)70793-7.
Liepmann posited that right hand preference relates to left hemisphere dominance for learned skilled movements. Limb apraxia, impairment of skilled movement, typically occurs in individuals with left hemisphere (LH) lesions. The occurrence of apraxia in right-handed individuals following right-hemisphere lesions appears to refute Liepmann's hypothesis. We studied the apraxia of a right-handed man, RF, following a right frontal lesion to determine whether his apraxia paralleled the apraxia seen following LH lesions. Results of behavioral testing indicated that, like individuals with apraxia following left frontal lesions, RF was better at gesture recognition than gesture production which was significantly impaired across tasks. Kinematic motion analyses of movement linearity, planarity, and the coupling of temporospatial aspects of movements substantiated the parallel impairments in RF and patients with LH apraxia. The impairment seen in our patient with crossed apraxia provides evidence for the fractionation of systems underlying hand preference and skilled movement.
利佩曼提出，右手偏好与左半球在学习熟练动作方面的优势有关。肢体失用症，即熟练动作的受损，通常发生在左半球（LH）受损的个体中。右半球受损的右利手个体出现失用症似乎驳斥了利佩曼的假说。我们研究了一名右利手男性RF在右额叶病变后的失用症，以确定他的失用症是否与左半球病变后出现的失用症相似。行为测试结果表明，与左额叶病变后出现失用症的个体一样，RF在手势识别方面比手势产生方面表现更好，而手势产生在各项任务中均受到显著损害。对运动线性、平面性以及运动时空方面耦合的运动学分析证实了RF与左半球失用症患者存在相似的损伤。我们这位交叉性失用症患者所出现的损伤为手偏好和熟练动作背后的系统分离提供了证据。
