Agnes P, Rozália K
Morphol Igazsagugyi Orv Sz. 1976 Oct;16(4):286-92.
A case of an olfactory neuroblastoma of a 5 years old child is reported. The tumour propagated into the intracranial space and produced cerebellar symptoms. Features of the neuroblastic cells, found in the cerebrospinal fluid and their alterations as an effect of the intrathecal therapy with Mathotrexat are analysed. Authors emphasize the differences of alterations of leukaemic and neuroblastic cells called into being by the Methotrexat therapy.
报告了一例5岁儿童嗅神经母细胞瘤病例。肿瘤蔓延至颅内空间并产生小脑症状。分析了脑脊液中发现的神经母细胞特征及其作为甲氨蝶呤鞘内治疗效果的变化。作者强调了甲氨蝶呤治疗引起的白血病细胞和神经母细胞变化的差异。