Péter A, Kádár A
Morphol Igazsagugyi Orv Sz. 1978 Jan;18(1):16-22.
Authors first in the literature described the surface profile of lymphocytes, plasma cells, phagocytes and malignant lymphoblasts of the liquor after intrathecal Methorexat therapy (i.thec.MTX). After prolonged treatment with MTX the mentioned cells were examined by SEM. The surface of the plasma cells and storage cells was found to be normal. Various stages of the phagocytosis could be observed. On the other hand the majority of lymphoblasts of leukaemic origin after the first administration of i.thec.MTX revealed damaged cell surfaces.
作者首次在文献中描述了鞘内注射甲氨蝶呤（鞘内MTX）治疗后脑脊液中淋巴细胞、浆细胞、吞噬细胞和恶性淋巴母细胞的表面形态。在用MTX进行长期治疗后，通过扫描电子显微镜对上述细胞进行了检查。发现浆细胞和储存细胞的表面正常。可以观察到吞噬作用的各个阶段。另一方面，首次鞘内注射MTX后，大多数白血病源性淋巴母细胞显示细胞表面受损。
