Bianchi C, Bonadio M, Donadio C, Tramonti G, Figus S, Papalexiou P
Experientia. 1976 Dec 15;32(12):1565-6. doi: 10.1007/BF01924456.
The renal heamodynamic effects of a single i.v. administration of tolamolol were studied in 9 hypertensive subjects. No change of GFR and ERPF was observed after tolamolol, while urine output decreased and urine creatinine concentration increased. A reduction of the heart rate was confirmed. Blood pressure was unchanged.
对9名高血压患者研究了单次静脉注射托拉洛尔的肾脏血流动力学效应。注射托拉洛尔后,肾小球滤过率(GFR)和有效肾血浆流量(ERPF)未观察到变化,而尿量减少,尿肌酐浓度增加。心率下降得到证实。血压未改变。