[甲状腺功能亢进症与糖尿病：10例非洲病例分析]

[Hyperthyroidism and diabetes mellitus: analysis of 10 African cases].

作者信息

Sidibé E H, Dia M, Toure-Sow H, Sow A M, Seck-Gassama S M, Ndoye R

机构信息

Service de Médecine Interne, Centre Marc Sankale, Clinique Médicale II, Dakar-Fann, Sénégal.

出版信息

Ann Endocrinol (Paris). 1999 Mar;60(1):33-9.

PMID:10374013

Abstract

This retrospective study of 10 patients with hyperthyroidisma and diabetes mellitus concerned 8 women and 2 men, aged from 15 to 77 years. The two disease developed at the same time in 8 cases. Diabetes mellitus occurred first in 2 cases. Common signs were loss of weight. Hyperthyroidism led to tachycardia at more than 100 bpm. Diarrhea was observed simultaneously in 2 cases and muscular weakness in 5. Goiter was found in 10 cases with a diffuse aspect. Graves' disease was diagnosed with exophthalmia in 9 cases and affected both eyes in 8. Elevated levels of thyroid hormones confirmed diagnosis in 8 cases. Diabetes was insulin-dependent in 3 cases and non-insulin dependent in the 7 others. IDDM patients (2 female and 1 male) were aged 15, 17 and 38. Keto acidosis was the first symptom in all cases. NIDDM patients (6 female and 1 male) were aged between 37 and 77.

摘要

这项对10例甲状腺功能亢进症合并糖尿病患者的回顾性研究涉及8名女性和2名男性，年龄在15至77岁之间。8例患者两种疾病同时发病。2例糖尿病先于甲状腺功能亢进症发病。常见症状为体重减轻。甲状腺功能亢进症导致心率超过100次/分钟。2例同时出现腹泻，5例出现肌无力。10例均发现有弥漫性甲状腺肿。9例格雷夫斯病患者伴有突眼，8例双眼受累。8例患者甲状腺激素水平升高确诊。3例糖尿病患者依赖胰岛素，其余7例不依赖胰岛素。胰岛素依赖型糖尿病患者（2名女性和1名男性）年龄分别为15岁、17岁和38岁。所有病例均以酮症酸中毒为首发症状。非胰岛素依赖型糖尿病患者（6名女性和1名男性）年龄在37至77岁之间。