B淋巴细胞上的共受体
Co-receptors on B lymphocytes.
作者信息
Tsubata T
机构信息
Department of Immunology, Medical Research Institute, Tokyo Medical andDental University, 1-5-45 Yushima, Bunkyo-ku, Tokyo, 113-8510, Japan.
出版信息
Curr Opin Immunol. 1999 Jun;11(3):249-55. doi: 10.1016/s0952-7915(99)80041-7.
Abstract
Co-receptors have been shown to regulate the antigen-receptor signaling threshold for B cell responses by modulating the activation of signaling molecules that are essential for transmitting a signal through the antigen-receptor. Co-receptors appear to modulate the signaling threshold for B cell tolerance distinctly from that for B cell activation.
摘要
共受体已被证明可通过调节信号分子的激活来调节B细胞反应的抗原受体信号阈值，这些信号分子对于通过抗原受体传递信号至关重要。共受体似乎以与B细胞激活不同的方式调节B细胞耐受的信号阈值。
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