McGillivray D, Ducharme F M, Charron Y, Mattimoe C, Treherne S
Departments of Pediatrics, Epidemiology, Biostatistics, and Biochemistry, Montreal Children's Hospital, McGill University, Montreal, Quebec, Canada.
Ann Emerg Med. 1999 Jul;34(1):58-63. doi: 10.1016/s0196-0644(99)70272-6.
In children aged 1 month to 18 years, we sought to examine the correlation between venous and arterialized capillary blood gas values, and to determine whether the source of blood sample influenced the interpretation of the acid-base status and clinical management.
In a cross-sectional study, venous and capillary blood gas values were simultaneously obtained in acutely ill well-perfused patients treated in a pediatric emergency department. Intraclass correlation coefficients for capillary and venous measured gas values were calculated. Crude agreement and intraobserver concordance were calculated for responses of 2 intensivists to the interpretation and clinical management questions, based on capillary and venous gas results.
Intraclass correlation coefficients for 78 capillary and venous paired measured gas values were.92 (pH), .80 (PCO 2 ), and .67 (PO 2 ). The alpha of concordance values between capillary and venous blood gas values, with 95% confidence intervals (CIs) were as follows, respectively, for physician A and B: interpretation, .61 (.47 to .73) and .48 (.41 to .55); need for bicarbonate,.85 (.73 to.97) and.80 (.72 to.88); and need for intubation .73 (.64 to .82), and .83 (.75 to .91).
In the well-perfused patient, we believe that venous samples are an acceptable alternative to capillary blood samples for determination of blood gas values and for making clinical management decisions.
在1个月至18岁的儿童中,我们试图研究静脉血与动脉化毛细血管血气值之间的相关性,并确定血样来源是否会影响酸碱状态的解读及临床管理。
在一项横断面研究中,对在儿科急诊科接受治疗的急性病且灌注良好的患者同时采集静脉血和毛细血管血气值。计算毛细血管和静脉测量血气值的组内相关系数。基于毛细血管和静脉血气结果,计算2名重症监护医生对解读和临床管理问题回答的粗略一致性和观察者内一致性。
78对毛细血管和静脉测量血气值的组内相关系数分别为:pH为0.92,PCO₂为0.80,PO₂为0.67。医生A和B的毛细血管和静脉血气值之间一致性值的α及95%置信区间(CI)分别如下:解读方面,分别为0.61(0.47至0.73)和0.48(0.41至0.55);是否需要碳酸氢盐方面,分别为0.85(0.73至0.97)和0.80(0.72至0.88);以及是否需要插管方面,分别为0.73(0.64至0.82)和0.83(0.75至0.91)。
对于灌注良好的患者,我们认为静脉血样是用于测定血气值及做出临床管理决策的毛细血管血样的可接受替代方案。