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社区获得性下呼吸道感染和肺炎

Lower respiratory tract infection and pneumonia in the community.

作者信息

Macfarlane J

机构信息

Respiratory Infection Unit, Nottingham City Hospital, and the University of Nottingham, United Kingdom.

出版信息

Semin Respir Infect. 1999 Jun;14(2):151-62.

Abstract

Community-acquired pneumonia (CAP) is common. There is no entirely satisfactory way of defining pneumonia using clinical criteria alone. New focal chest signs on examination in the presence of a systemic illness that is suggestive of a lower respiratory tract infection seems to be the best clinical finding that indicates pneumonia. Progress has been made in identifying simple clinical features that relate to prognosis and allow the general practitioner to decide whether care in the community is appropriate or hospital referral is required. Psychosocial factors for the patient will also remain important. Most patients who have CAP that is mild enough to be managed in the community will require few, if any, investigations. A chest radiograph is appropriate in all patients to exclude an underlying lung tumor. Measurement of surrogate markers of acute infection, such as C-reactive protein, may prove useful to the general practitioner if near testing were to become feasible. The antibiotic management for CAP for patients well enough to be managed at home can be simple and logical, providing general practitioners have some knowledge regarding likely pathogens and etiologic and epidemiological clues. Any antibiotic chosen must suppress Streptococcus pneumoniae, which remains the most common cause of CAP.

摘要

社区获得性肺炎(CAP)很常见。仅使用临床标准来定义肺炎并没有完全令人满意的方法。在存在提示下呼吸道感染的全身性疾病时,检查发现新的肺部局灶性体征似乎是提示肺炎的最佳临床发现。在识别与预后相关的简单临床特征方面已经取得了进展,这使得全科医生能够决定患者在社区接受治疗是否合适,还是需要转诊至医院。患者的社会心理因素也仍然很重要。大多数病情较轻、可在社区管理的CAP患者几乎不需要进行检查(如果需要的话)。所有患者都应进行胸部X线检查以排除潜在的肺部肿瘤。如果即时检测变得可行,测量急性感染的替代标志物,如C反应蛋白,可能对全科医生有用。对于病情稳定、可在家中治疗的CAP患者,抗生素治疗可以简单且合理,前提是全科医生对可能的病原体以及病因和流行病学线索有一定了解。所选用的任何抗生素都必须抑制肺炎链球菌,它仍然是CAP最常见的病因。

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