Sandhu J S, Campbell P M, Preiksaitis J K, Carriere K C, Hessel P A
Department of Public Health Sciences, University of Alberta, Edmonton.
Can J Public Health. 1999 May-Jun;90(3):201-4. doi: 10.1007/BF03404507.
The purpose of this analysis was to assess the validity of self-reported transfusion histories in dialysis patients. Using data from a cross-sectional study of a dialysis population being investigated for hepatitis C virus (HCV) infection, the correspondence between self-reported transfusion history and transfusion records was explored. Demographic data and dialysis histories were examined in relation to the accuracy of self-reports. Overall, the questionnaire data and the blood bank records agreed for 89% of participants. The Kappa statistic was 0.72 (95% CI: 0.61, 0.83) indicating an acceptable level of agreement. The effect of non-differential exposure misclassification on the risk estimates for transfusion history as a determinant of HCV infection is demonstrated. Exploring the discrepancies between self-reports and documented transfusion histories underlines the need to communicate clearly medical interventions in chronically ill patients. Additionally, it suggests that studies into transfusion-acquired blood-borne pathogens should use all available information sources to establish exposure.
本分析的目的是评估透析患者自我报告的输血史的有效性。利用对一组接受丙型肝炎病毒（HCV）感染调查的透析人群进行横断面研究的数据，探讨了自我报告的输血史与输血记录之间的对应关系。研究了人口统计学数据和透析史与自我报告准确性之间的关系。总体而言，89%的参与者的问卷数据与血库记录一致。Kappa统计量为0.72（95%CI：0.61，0.83），表明一致性水平可接受。证明了非差异性暴露错误分类对作为HCV感染决定因素的输血史风险估计的影响。探究自我报告与记录的输血史之间的差异突出了向慢性病患者清晰传达医疗干预措施的必要性。此外，这表明对输血获得的血源性病原体的研究应使用所有可用信息来源来确定暴露情况。
