Nyklícek I, Vingerhoets A J, Van Heck G L
Department of Psychology, Tilburg University, The Netherlands.
Biol Psychol. 1999 Jun;50(2):127-42. doi: 10.1016/s0301-0511(99)00006-x.
Repeatedly, hypertensives have been found to appraise physical stressors as less aversive than normotensives. The main aim of the present study was to examine the effects of gender and cardiovascular reactivity in the relationship between hypertension and appraisal of pain. Forty-two unmedicated hypertensives and 21 normotensive controls of both genders were exposed to an electric current stimulus, while various cardiovascular parameters and prestressor anxiety were measured. In general, hypertensive women, but not men, showed diminished pain sensitivity compared to their normotensive counterparts. When the analyses were repeated with controlling for cardiovascular reactivity, the between-group effects were no longer significant. The results indicate that (i) profound gender differences exist in hypertension-related pain sensitivity and (ii) these effects seem to be mediated, at least partly, by cardiovascular reactivity.
研究反复发现，高血压患者比血压正常者更不厌恶身体应激源。本研究的主要目的是检验性别和心血管反应性在高血压与疼痛评估关系中的作用。42名未服药的高血压患者和21名男女血压正常的对照者接受电流刺激，同时测量各种心血管参数和应激前焦虑情况。总体而言，与血压正常的女性相比，高血压女性的疼痛敏感性降低，但男性并非如此。在控制心血管反应性后重复分析，组间效应不再显著。结果表明：（i）高血压相关的疼痛敏感性存在显著的性别差异；（ii）这些效应似乎至少部分由心血管反应性介导。
