Koito H, Nakamura C, Suzuki J, Takahashi H, Iwasaka T
Second Department of Internal Medicine, Cardiovascular Center, Kansai Medical University, Moriguchi, Japan.
Jpn Circ J. 1999 Jun;63(6):490-2. doi: 10.1253/jcj.63.490.
A report is presented of a liquefaction necrosis of mitral annular calcification in a patient with chronic renal failure and secondary hyperparathyroidism who had been managed by hemodialysis for 11 years. The mass was echogenic with an echo-lucent area inside, high density on computed tomography and low intensity on magnetic resonance imaging. The uptake of gallium-67 (67Ga)-citrate and the bone agent technetium-99m-methylene diphosphate (99mTc-MDP) was seen in the mass. These findings were compatible with liquefaction necrosis of the mitral annular calcification. After treatment with low calcium concentration hemodialysis, the size of the mass reduced with disappearance of the echo-lucent area on the echocardiography and there was no uptake of 67Ga-citrate or 99mTc-MDP. Liquefaction necrosis might be the early and reversible form of mitral annular calcification. When a tumorlike echogenic mass at the base of mitral leaflets is seen in patients with predisposing factors for mitral annular calcification, consider the possibility of this specific form of mitral annular calcification in order to avoid any unnecessary surgical intervention.
报告了一例慢性肾衰竭和继发性甲状旁腺功能亢进患者的二尖瓣环钙化液化坏死病例,该患者已接受血液透析治疗11年。肿块呈回声增强,内部有一无回声区,计算机断层扫描显示高密度,磁共振成像显示低信号强度。在肿块中可见镓-67(67Ga)枸橼酸盐和骨显像剂锝-99m亚甲基二膦酸盐(99mTc-MDP)摄取。这些发现符合二尖瓣环钙化的液化坏死。采用低钙浓度血液透析治疗后,肿块大小缩小,超声心动图上无回声区消失,且67Ga枸橼酸盐或99mTc-MDP无摄取。液化坏死可能是二尖瓣环钙化的早期可逆形式。当在有二尖瓣环钙化易感因素的患者中发现二尖瓣叶基部有肿瘤样回声肿块时,应考虑这种特殊形式的二尖瓣环钙化的可能性,以避免任何不必要的手术干预。