Akram Mohammad, Hasanin Adel M
Department of Cardiology, Arryan Hospital, Dr. Sulaiman Al Habib Medical Group, Riyadh, Saudi Arabia.
J Saudi Heart Assoc. 2012 Jul;24(3):205-8. doi: 10.1016/j.jsha.2012.02.003. Epub 2012 Feb 14.
Caseous mitral annular calcification (CMAC) is a variant of mitral annular calcification (MAC) with a central liquefaction necrosis. The echocardiographic prevalence of CMAC is approximately 0.6% in patients with MAC and 0.06-0.07% in large series of patients of all ages. However, the prevalence in necropsy series has been reported to be 2.7%, which indicates that this condition is yet under-recognized. Furthermore CMAC is probably underappreciated as a source of potentially serious conditions. We report a case of recent stroke associated with CMAC diagnosed by trans-thoracic and confirmed by trans-esophageal echocardiogram (TEE). The importance of correct diagnosis of CMAC extends beyond the possible complications; since several misdiagnoses of CMAC as abscesses and cardiac tumors have been reported leading to inappropriate interventions.
干酪样二尖瓣环钙化(CMAC)是二尖瓣环钙化(MAC)的一种变体,伴有中央液化坏死。在MAC患者中,CMAC的超声心动图患病率约为0.6%,在所有年龄段的大量患者系列中为0.06 - 0.07%。然而,尸检系列中的患病率报告为2.7%,这表明这种情况尚未得到充分认识。此外,CMAC作为潜在严重疾病的来源可能未得到充分重视。我们报告一例近期与CMAC相关的中风病例,经胸诊断并经食管超声心动图(TEE)证实。正确诊断CMAC的重要性不仅在于可能的并发症;因为已有报道称CMAC被误诊为脓肿和心脏肿瘤,从而导致不适当的干预。