Polevaya Y, Ermolina I, Schlesinger M, Ginzburg B Z, Feldman Y
Department of Applied Physics, Hebrew University of Jerusalem, 91904, Jerusalem, Israel.
Biochim Biophys Acta. 1999 Jul 15;1419(2):257-71. doi: 10.1016/s0005-2736(99)00072-3.
The dielectric properties of human lymphocyte suspensions were studied by time domain dielectric spectroscopy (TDDS). Nine populations of malignant and normal lymphocytes were investigated. Analysis of the dielectric parameters of cell structural parts were performed in the framework of Maxwell-Wagner mixture formula and the double-shell model of cell. The specific capacitance of the cell membranes was estimated by the Hanai-Asami-Koisumi formula. It was shown that the dielectric permittivity, capacitance and conductivity values of cell membranes are higher for normal lymphocytes than for the malignant ones. The difference of the same parameters for normal B- and T-cells is also discussed.
通过时域介电谱（TDDS）研究了人淋巴细胞悬液的介电特性。对9种恶性和正常淋巴细胞群体进行了研究。在麦克斯韦-瓦格纳混合公式和细胞双壳模型的框架内，对细胞结构部分的介电参数进行了分析。通过花井-浅见-小泉公式估算了细胞膜的比电容。结果表明，正常淋巴细胞细胞膜的介电常数、电容和电导率值高于恶性淋巴细胞。还讨论了正常B细胞和T细胞相同参数的差异。
