Chen K T, Chen C J, Gregg E W, Williamson D F, Narayan K M
Field Epidemiology Training Program, National Institute of Preventive Medicine, Department of Health, Taipei, Taiwan, ROC.
Diabetes Res Clin Pract. 1999 Apr;44(1):59-69. doi: 10.1016/s0168-8227(99)00025-x.
The purpose of this study was to estimate the prevalence of type 2 diabetes and impaired fasting glucose (IFG) in Penghu, Taiwan and compare these estimates with those of the US (NHANES III). Diabetes and IFG (American Diabetes Association criteria, 1997) were assessed among a stratified random sample of 2500 residents of Penghu Islands, Taiwan. The prevalence (age-adjusted to world adult population) of diabetes and IFG were 16.8% (95% CI 15.0-18.6) and 21.0% (95% CI 19.0-23.0), respectively, among Penghu Islanders in Taiwan. Age sex-specific diabetes prevalence ranged from 10.0% in men aged 40-49 years to 29.4% in women aged 60-69 years. Prevalence of IFG ranged from 14.7% in women aged 40-49 years to 30.7% in men aged 50-59 years. Age, body mass index (BMI), and family history of diabetes were each independently associated with both diabetes and IFG. In addition, female gender, apolipoprotein B and triglyceride concentrations were associated with diabetes, and hypertension and apolipoprotein B concentration with IFG. Among persons > or = 40 years in Penghu, Taiwan, the prevalence of diabetes is up to a third higher and the prevalence of IFG is up to three times higher than comparably aged Americans, despite their having a mean BMI 2.2-3.2 kg/m2 lower than Americans. The alarmingly high prevalence of IFG in Taiwan may indicate an emerging diabetes epidemic.
本研究旨在估算台湾澎湖地区2型糖尿病和空腹血糖受损（IFG）的患病率，并将这些估算值与美国（第三次国家健康和营养检查调查，即NHANES III）的结果进行比较。我们在台湾澎湖列岛2500名居民的分层随机样本中评估了糖尿病和IFG（采用1997年美国糖尿病协会标准）。台湾澎湖岛居民中，糖尿病和IFG的患病率（年龄调整至世界成年人口）分别为16.8%（95%可信区间15.0 - 18.6）和21.0%（95%可信区间19.0 - 23.0）。特定年龄和性别的糖尿病患病率从40 - 49岁男性的10.0%到60 - 69岁女性的29.4%不等。IFG的患病率从40 - 49岁女性的14.7%到50 - 59岁男性的30.7%不等。年龄、体重指数（BMI）和糖尿病家族史均分别与糖尿病和IFG独立相关。此外，女性性别、载脂蛋白B和甘油三酯浓度与糖尿病相关，高血压和载脂蛋白B浓度与IFG相关。在台湾澎湖40岁及以上人群中，尽管他们的平均BMI比美国人低2.2 - 3.2 kg/m²，但糖尿病患病率比年龄相仿的美国人高出多达三分之一，IFG患病率比美国人高出多达三倍。台湾IFG惊人的高患病率可能预示着糖尿病流行的出现。
