Ylä-Herttuala S
A.I. Virtanen Institute, University of Kuopio, Finland.
Ann N Y Acad Sci. 1999 Jun 30;874:134-7. doi: 10.1111/j.1749-6632.1999.tb09231.x.
A brief review of recent findings regarding the role of oxidized low-density lipoproteins (Ox-LDL) in atherogenesis. Lipid peroxidation and oxidative damage to LDL make arteries susceptible to chronic inflammation, which is known to cause alterations in arterial gene expression and promote lesion development. Treatment protocols implementing antioxidants for preventing cardiovascular diseases are suggested.
对氧化型低密度脂蛋白（Ox-LDL）在动脉粥样硬化形成中作用的近期研究结果的简要综述。脂质过氧化和LDL的氧化损伤使动脉易患慢性炎症，已知慢性炎症会导致动脉基因表达改变并促进病变发展。建议实施使用抗氧化剂预防心血管疾病的治疗方案。
