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一只混血犬的凝血因子VII缺乏症。

Factor VII deficiency in a mixed breed dog.

作者信息

Macpherson R, Scherer J, Ross M L, Gentry P A

机构信息

Western Animal Clinic, London, Ontario.

出版信息

Can Vet J. 1999 Jul;40(7):503-5.

PMID:10416073
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1539753/
Abstract

Abnormal bleeding following routine orchectomy of a 5-month-old mixed breed was determined to be due to factor VII deficiency. Although pedigree information was unavailable, failure to respond to vitamin K therapy and the absence of a plasma coagulation inhibitor suggested that the factor VII deficiency was likely inherited rather than acquired.

摘要

一只5个月大的混种犬在进行常规睾丸切除术后出现异常出血,经诊断是由于凝血因子VII缺乏所致。尽管无法获取系谱信息,但对维生素K治疗无反应以及不存在血浆凝血抑制剂表明,凝血因子VII缺乏很可能是遗传性的而非后天获得性的。

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1
Factor VII deficiency in a mixed breed dog.一只混血犬的凝血因子VII缺乏症。
Can Vet J. 1999 Jul;40(7):503-5.
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[Congenital deficiency of factor VII in a canine family].[犬类家族中因子VII的先天性缺乏]
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引用本文的文献

1
Canine factor VII deficiency: lessons learned in applying methods-based laboratory proficiency testing.犬因子VII缺乏症:在基于方法的实验室能力验证中获得的经验教训。
J Vet Diagn Invest. 2019 Mar;31(2):276-279. doi: 10.1177/1040638718825281. Epub 2019 Jan 19.
2
Inadvertent propagation of factor VII deficiency in a canine mucopolysaccharidosis type I research breeding colony.在一个犬类I型粘多糖贮积症研究繁殖群体中意外传播的凝血因子VII缺乏症。
Comp Med. 2009 Aug;59(4):378-82.

本文引用的文献

1
Optimization of prothrombin time measurements in canine plasma.犬血浆中凝血酶原时间测量的优化
Am J Vet Res. 1997 Mar;58(3):236-41.
2
Benign and secondary progressive multiple sclerosis: a preliminary quantitative MRI study.良性与继发进展型多发性硬化症:一项初步的定量MRI研究。
J Neurol. 1994 Feb;241(4):246-51. doi: 10.1007/BF00863776.
3
Buccal mucosa bleeding time is prolonged in canine models of primary hemostatic disorders.在原发性止血障碍的犬模型中,颊黏膜出血时间会延长。
Thromb Haemost. 1993 Nov 15;70(5):777-80.
4
Canine factor-VII deficiency: experience with a modified thrombotest method in distinguishing between the genotypes.犬因子 VII 缺乏症:使用改良凝血检测法区分基因型的经验。
Res Vet Sci. 1974 Mar;16(2):228-39.
5
The clinical aspects of canine factor-VII deficiency including some case histories.犬因子VII缺乏症的临床情况,包括一些病例史。
J Small Anim Pract. 1974 Apr;15(4):229-39. doi: 10.1111/j.1748-5827.1974.tb05687.x.
6
Normal values of coagulation in canine blood.
Haemostasis. 1985;15(5):318-23. doi: 10.1159/000215166.
7
In vivo studies of the role of factor VII in hemostasis.凝血因子VII在止血过程中作用的体内研究。
Blood. 1985 May;65(5):1197-200.
8
[Congenital deficiency of factor VII in a canine family].[犬类家族中因子VII的先天性缺乏]
Jikken Dobutsu. 1987 Oct;36(4):423-30. doi: 10.1538/expanim1978.36.4_423.
9
Hereditary blood coagulation factor-VII deficiency: a comparison of the defect in beagles from several sources.
Comp Biochem Physiol A Comp Physiol. 1988;89(3):461-4. doi: 10.1016/0300-9629(88)91057-2.
10
Diagnosis of classic hemophilia (hemophilia A) in a standard poodle.一只标准贵宾犬患典型血友病(甲型血友病)的诊断
Can Vet J. 1977 Mar;18(3):79-81.