Goettsch W G, Goossens H, de Neeling A J, Sprenger M J
Centrum voor Infectieziekten Epidemiologie, Rijksinstituut voor Volksgezondheid en Milieu, Bilthoven.
Ned Tijdschr Geneeskd. 1999 Jun 19;143(25):1296-9.
The frequency of resistance to antibiotics among community acquired pathogens and the number of drugs to which they are resistant are increasing world wide. Antimicrobial resistance in the Netherlands is still low. Resistance to antimicrobial drugs is clearly linked to consumption of antibiotics within and outside of the hospital. Use of antibiotics in veterinary medicine may also contribute to the occurrence of antimicrobial resistance in human pathogens. Strategies to limit the spread of resistant strains should include encouraging the judicious use of antimicrobial agents. Guidelines for antibiotic therapy should be based on results derived from well designed surveillance studies.
全球范围内,社区获得性病原体对抗生素的耐药频率及其耐药药物的数量都在增加。荷兰的抗菌药物耐药性仍然较低。抗菌药物耐药性与医院内外抗生素的使用明显相关。兽医学中抗生素的使用也可能导致人类病原体产生抗菌药物耐药性。限制耐药菌株传播的策略应包括鼓励合理使用抗菌药物。抗生素治疗指南应基于精心设计的监测研究结果。