Ali R M, Houghton P J
Planta Med. 1999 Jun;65(5):455-7. doi: 10.1055/s-2006-960811.
The dichloromethane extract of the stem of jacaranda filicifolia Don. showed inhibitory activity in vitro against soybean 5-lipoxygenase. Systematic fractionation to isolate the compounds responsible resulted in the isolation of three active compounds, 2 alpha, 3 alpha-dihydroxyurs-12-en-28-oic acid, beta-sitosterol, and one of which was new which was characterised as 2-(4-hydroxyphenyl)ethyl 1-dodecyloctadecanoate. This type of compound has not previously been reported to inhibit lipoxygenase.
蓝花楹(Jacaranda filicifolia Don.)茎的二氯甲烷提取物在体外对大豆5-脂氧合酶表现出抑制活性。通过系统分级分离以分离出起作用的化合物,结果分离出三种活性化合物,2α,3α-二羟基乌苏-12-烯-28-酸、β-谷甾醇,其中一种是新化合物,其被鉴定为2-(4-羟基苯基)乙基1-十二烷基十八烷酸酯。此前尚未报道过此类化合物具有抑制脂氧合酶的作用。