Yawer Mirza Arfan, Ahmed Ejaz, Malik Abdul, Ashraf Muhammad, Rasool Muhammad Azam, Afza Nighat
International Centre for Chemical Sciences, HEJ Research Institute of Chemistry, University of Karachi, Karachi-75270, Pakistan.
Chem Biodivers. 2007 Jul;4(7):1578-85. doi: 10.1002/cbdv.200790137.
Calligonolides A (1) and B (2), two new butanolides, and a new steroidal ester, 3, have been isolated from the whole plant of Calligonum polygonoides, together with four known compounds, tetracosan-4-olide, beta-sitosterol and its glucoside, and ursolic acid. Their structures were elucidated by spectroscopic and mass-spectrometric studies. Compounds 1-3 showed moderate inhibitory potential against lipoxygenase from soybean.
从戈壁霸王全草中分离得到两个新的丁内酯类化合物沙拐枣内酯A(1)和B(2)、一个新的甾体酯类化合物3,以及四个已知化合物:二十四烷-4-内酯、β-谷甾醇及其糖苷和熊果酸。通过光谱和质谱研究确定了它们的结构。化合物1 - 3对大豆脂氧合酶显示出中等抑制活性。