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[急性期复发性轻度颅脑创伤的临床免疫学研究]

[A clinico-immunological study in recurrent mild craniocerebral trauma in the acute period].

作者信息

Gorbunov V I

出版信息

Zh Vopr Neirokhir Im N N Burdenko. 1999 Apr-Jun(2):17-21.

PMID:10420540
Abstract

Comparative clinical (X-ray study, computed tomography, echoencephalography, electroencephalography, electrocardiography, examination of the fundus of the eye, lumbar puncture) and immunological (examination of cellular and humoral immunities, neurosensitization) studies were conducted in 98 patients with the first mild brain injury and 92 with repeated injury. Clinical and immunological parameters became worse in patients with repeated brain injury at week 3, which shows the development of autoimmune autoaggressive reactions in the sensitized body. These patients should be referred to as a risk group of disease progression and they should be given immunomodulating therapy.

摘要

对98例首次轻度脑损伤患者和92例重复性脑损伤患者进行了临床比较研究(X线检查、计算机断层扫描、脑回波描记术、脑电图、心电图、眼底检查、腰椎穿刺)和免疫学研究(细胞免疫和体液免疫检查、神经致敏)。在第3周时,重复性脑损伤患者的临床和免疫学参数变差,这表明致敏机体中自身免疫性自攻击反应的发展。这些患者应被视为疾病进展的风险组,应给予免疫调节治疗。

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