Morimoto K, Fujimoto M
Second Department of Surgery, Osaka City University Medical School.
Kansenshogaku Zasshi. 1999 Jun;73(6):584-92. doi: 10.11150/kansenshogakuzasshi1970.73.584.
In the Kinki District (Hyogo area, Osaka City area, Osaka Outskirts area, Nara area and Wakayama area), a questionnaire survey of 30 institutions was conducted for methicillin-resistant Staphylococcus aureus (MRSA) and penicillin-resistant Streptococcus pneumoniae (PRSP). Median number of their bed was 500 ranging 0 to 1076, 3239 (56%) of the 5815 strains of S. aureus were methicillin-resistant. Although no different prevalence was found among the areas, they were predominantly isolated from sputum of inpatients more than from outpatients, 336 (44%) of the 763 strains of S. pneumoniae were penicillin-resistant. The prevalence rate was the highest in the outpatients in Osaka outskirts. Almost all strains of MRSA were sensitive to vancomycin (VCM) and sulfamethoxazole trimethoprim (ST). Resistant strains were observed in 2% against arbekacin, 6% against amikacin, 44% against minocycline (MINO), and in 54% against gentamicin (GM). Almost all strains of PRSP were sensitive to VCM and ST. Resistant strains were observed in 75% against erythromycin, 50% against MINO, and 75% against GM. This survey identified the trend of hospital infection for MRSA and community infection for PRSP, and sensitive drugs for the treatment.
在近畿地区（兵库地区、大阪市地区、大阪郊区、奈良地区和和歌山地区），针对耐甲氧西林金黄色葡萄球菌（MRSA）和耐青霉素肺炎链球菌（PRSP）对30家机构进行了问卷调查。这些机构的床位中位数为500张（范围为0至1076张），在5815株金黄色葡萄球菌菌株中，3239株（56%）对甲氧西林耐药。尽管各地区之间未发现不同的流行率，但这些菌株主要从住院患者的痰液中分离得到，而非门诊患者，在763株肺炎链球菌菌株中，336株（44%）对青霉素耐药。在大阪郊区的门诊患者中，耐药率最高。几乎所有MRSA菌株对万古霉素（VCM）和复方磺胺甲恶唑（ST）敏感。观察到2%的菌株对阿贝卡星耐药，6%对阿米卡星耐药，44%对米诺环素（MINO）耐药，54%对庆大霉素（GM）耐药。几乎所有PRSP菌株对VCM和ST敏感。观察到75%的菌株对红霉素耐药，50%对MINO耐药，75%对GM耐药。这项调查确定了MRSA的医院感染趋势和PRSP的社区感染趋势以及治疗的敏感药物。
