Westbury C F, Zatorre R J, Evans A C
Department of Neuropsychology and Cognitive Neuroscience, Montreal Neurological Institute and Hospital, Quebec, Canada.
Cereb Cortex. 1999 Jun;9(4):392-405. doi: 10.1093/cercor/9.4.392.
The acquisition of definitive evidence for systematic hemispheric asymmetries in the size of the planum temporale (PT) has been restricted by difficulties in identifying, standardizing and measuring the region of interest. In this paper an operational definition for identifying the problematic posterior border of the PT on magnetic resonance imaging (MRI) scans is proposed. An interactive voxel-painting program was used to identify and label the PT simultaneously in horizontal, sagittal and coronal planes in MRI scans, transformed into the standardized Talairach-Tournoux stereo-taxic space, from 50 normal right-handed volunteers. Both grey matter volume and cortical surface area of the PT were measured, while controlling for individual variation in overall brain shape and volume. The labeled tissue was averaged together to produce a probability map in standardized space of the region of interest. The PT region is highly variable, with no single voxel being labeled with a probability of >65%. In this study there were no significant hemispheric differences in volume or area of the PT. An asymmetry in area and volume was introduced by using an alternative method - the 'knife-cut' method - for identifying the posterior border. Implications for functional neuroimaging of the PT are discussed.
颞平面（PT）大小存在系统性半球不对称的确切证据的获取，一直受到识别、标准化和测量感兴趣区域的困难所限制。本文提出了一种在磁共振成像（MRI）扫描中识别PT有问题的后边界的操作定义。使用一个交互式体素绘制程序，在50名正常右利手志愿者的MRI扫描的水平、矢状和冠状平面中同时识别和标记PT，并将其转换到标准化的Talairach-Tournoux立体定向空间。在控制整体脑形状和体积的个体差异的同时，测量了PT的灰质体积和皮质表面积。将标记的组织进行平均，以在感兴趣区域的标准化空间中生成概率图。PT区域高度可变，没有单个体素的标记概率大于65%。在本研究中，PT的体积或面积没有显著的半球差异。通过使用另一种方法——“刀切”法——来识别后边界，引入了面积和体积的不对称性。讨论了对PT功能神经成像的影响。
