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果蝇中与卫星DNA相邻的一个基因。

A gene adjacent to satellite DNA in Drosophila melanogaster.

作者信息

Carlson M, Brutlag D

出版信息

Proc Natl Acad Sci U S A. 1978 Dec;75(12):5898-902. doi: 10.1073/pnas.75.12.5898.

Abstract

Several copies of a sequence adjacent to 1.688 g/cm3 satellite DNA in the Drosophila melanogaster genome have been isolated by molecular cloning. This sequence, called the Dm142 gene, is homologous to a 1.6-kilobase RNA found in both D. melanogaster embryos and tissue culture cells. One cloned DNA segment includes two copies of the Dm142 gene and 1.688 g/cm3 satellite DNA sequences, which are located between and flanking both gene copies. The Dm142 gene is repeated many times in the D. melanogaster genome, and some copies are not flanked by 1,688 g/cm3 satellite DNA.

摘要

通过分子克隆,已从黑腹果蝇基因组中分离出几个与1.688克/立方厘米卫星DNA相邻的序列拷贝。这个序列被称为Dm142基因,与在黑腹果蝇胚胎和组织培养细胞中都发现的一种1.6千碱基RNA同源。一个克隆的DNA片段包含两个Dm142基因拷贝和1.688克/立方厘米卫星DNA序列,它们位于两个基因拷贝之间并在其两侧。Dm142基因在黑腹果蝇基因组中重复多次,一些拷贝两侧没有1.688克/立方厘米卫星DNA。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e83e/393083/afdf366c23ac/pnas00022-0163-a.jpg

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