Chen Y, Dales R, Krewski D, Breithaupt K
Department of Epidemiology and Community Medicine, Faculty of Medicine, University of Ottawa, Ontario, Canada.
Am J Epidemiol. 1999 Aug 1;150(3):255-62. doi: 10.1093/oxfordjournals.aje.a009996.
To assess smoking, obesity, and other risk factors for asthma, the authors examined 17,605 subjects aged 12 years or more who participated in the National Population Health Survey in 1994-1995. Asthma was considered present if an affirmative response was given to the question, "Do you have asthma diagnosed by a health professional?" The authors used analytic weights incorporating a design effect to take the complex survey design into account. The prevalence of asthma was 10.4% for males and 11.2% for females aged 12-24 years. Among the subjects aged 25 years or more, the prevalence varied from 4.1% to 5.8% for men and from 4.9% to 6.4% for women. Female smokers demonstrated a 1.7-fold increase in the prevalence of asthma compared with female nonsmokers, with the smoking effect more pronounced among female children and young adults. In contrast, there was no significant relation between smoking and asthma in males. The prevalence of asthma increased with increasing body mass index in females, but not in males. Immigrant status, history of allergy, and household income were significant predictors for both genders. Low household income was associated with a higher prevalence of asthma in men and women.
为评估吸烟、肥胖及其他哮喘风险因素,作者对1994 - 1995年参加全国人口健康调查的17605名12岁及以上受试者进行了检查。如果对“你是否有经健康专业人员诊断的哮喘?”这一问题给出肯定回答,则认为患有哮喘。作者使用了纳入设计效应的分析权重,以考虑复杂的调查设计。12 - 24岁男性哮喘患病率为10.4%,女性为11.2%。在25岁及以上的受试者中,男性患病率在4.1%至5.8%之间,女性在4.9%至6.4%之间。与女性非吸烟者相比,女性吸烟者哮喘患病率增加了1.7倍,吸烟效应在女童和年轻女性中更为明显。相比之下,男性吸烟与哮喘之间无显著关联。女性哮喘患病率随体重指数增加而上升,但男性并非如此。移民身份、过敏史和家庭收入是两性哮喘的重要预测因素。低家庭收入与男性和女性较高的哮喘患病率相关。