Fu Y X, Li W H
Human Genetics Center, SPH, University of Texas, Houston, Texas 77225, USA.
Theor Popul Biol. 1999 Aug;56(1):1-10. doi: 10.1006/tpbi.1999.1421.
Coalescent theory represents the most significant progress in theoretical population genetics in the past two decades of this century. It is now widely recognized as a cornerstone for rigorous statistical analyses of molecular data from populations. In the future, challenges from the rapidly expanding body of molecular data will continue to inject fresh blood into the development of coalescent theory. As the 21st century looms, we review recent progress in coalescent theory and discuss some prospects for future developments, particularly with regard to human population genetics.
合并理论是本世纪过去二十年里理论群体遗传学中最重要的进展。现在它已被广泛认可为对群体分子数据进行严格统计分析的基石。未来，来自迅速增长的分子数据的挑战将继续为合并理论的发展注入新鲜血液。随着21世纪的临近，我们回顾合并理论的近期进展，并讨论未来发展的一些前景，特别是关于人类群体遗传学方面的。
