Wang W, Mei X F, Du L, Lu S W, Fu X M, Wang Y H
Anhui Institute of Stereotactic Neurosurgery, Anhui Provincial Hospital, Hefei, People's Republic of China.
J Neural Transm (Vienna). 1999;106(5-6):559-68. doi: 10.1007/s007020050179.
Eighty-three subjects (47 women and 36 men) were submitted to Plutchik-van Praag's (PVP) depression inventory, Zuckerman's sensation seeking scales and Zuckerman-Kuhlman's personality inventory, and underwent auditory evoked potential studies using clicks at 4 different intensities of 70, 80, 90 and 100 dB. The clicks were delivered at an interstimulus interval varying randomly around 0.5s, which can elicit an obligatory subcomponent of N1. The P2 latency was significantly prolonged at the highest intensity. The intensity dependence of peak-to-peak N1-P2 and of baseline-to-peak N1 and P2 components was pronounced and the majority of subjects were augmenters. The N1 latency elicited at 70 dB was positively correlated with the thrill and adventure seeking, which then correlated the activity. The correlation suggests that a lower level of arousal, as indicated by prolonged N1 latency, would lead one to seek higher stimulation, such as the augmented response, the increased desire of physical thrill and adventure and elevated activity. This study, therefore, supports Zuckerman's theory that a sensation seeking personality is related to cortical arousal level.
83名受试者（47名女性和36名男性）接受了普拉奇克-范普拉格（PVP）抑郁量表、朱克曼感觉寻求量表和朱克曼-库尔曼人格量表的测试，并使用70、80、90和100分贝4种不同强度的短声进行了听觉诱发电位研究。短声以随机分布在0.5秒左右的刺激间隔呈现，这可以引出一个必然出现的N1子成分。在最高强度时，P2潜伏期显著延长。峰峰值N1-P2以及基线到峰值的N1和P2成分的强度依赖性明显，大多数受试者为增强者。70分贝时引出的N1潜伏期与寻求刺激和冒险呈正相关，而这又与活动相关。这种相关性表明，如N1潜伏期延长所示的较低唤醒水平会导致一个人寻求更高的刺激，如增强反应、对身体刺激和冒险的渴望增加以及活动增加。因此，本研究支持朱克曼的理论，即感觉寻求型人格与皮层唤醒水平有关。
