Rop P P, Sournac M H, Elie I, Burle J, Fornaris M
Laboratoire de Police Scientifique de Marseille, France.
J Anal Toxicol. 1999 Jul-Aug;23(4):294-6. doi: 10.1093/jat/23.4.294.
A fatality following ingestion of sulpiride is presented. The drug was identified and quantitated in postmortem blood by gas chromatography-mass spectrometry and high-performance liquid chromatography with diode-array detection. The concentration was 38 microg/mL, which was in excess of 34 times the therapeutic concentration of sulpiride. For other associated drugs, their concentrations were in their therapeutic ranges.
本文报告了一例因服用舒必利致死的病例。通过气相色谱-质谱联用仪和配有二极管阵列检测的高效液相色谱法对死后血液中的该药物进行了鉴定和定量分析。其浓度为38微克/毫升,超过舒必利治疗浓度的34倍。对于其他相关药物,其浓度处于治疗范围内。