Pardhan S, Beesley J
Department of Optometry, Bradford University, West Yorkshire, United Kingdom.
J Refract Surg. 1999 Jul-Aug;15(4):469-74. doi: 10.3928/1081-597X-19990701-13.
A decrease in the vertex radius occurs with aging. The aim of this study was to investigate whether the degree of flattening from the vertex to the periphery of the cornea, ie, the surface profile, also changes with age.
A "p" value (a parameter that denotes the rate of flattening from the apex to the limbus) and vertex radius were measured in the horizontal meridian in a group of young and older subjects using the EyeSys videokeratoscope and the Topcon autokeratometer.
With EyeSys data, horizontal vertex radius and p value were computed by means of plotting a graph of r2 (sagittal radius) versus y2 (perpendicular distance from the instrument optical axis). For Topcon data, previously derived equations were used. Mean vertex radii in the younger Topcon autokeratometer group was 7.91+/-0.31 and for the EyeSys videokeratoscope was 7.98+/-0.31. For the older group, Topcon mean vertex radii was 7.68+/-0.22 and EyeSys mean was 7.74+/-0.24. Mean p value in the younger group was 0.66+/-0.09 for the Topcon and 0.78+/-0.07 for the EyeSys. In the older group, mean vertex radii was 0.74+/-0.07 for the Topcon and 0.86+/-0.07 for the EyeSys.
Vertex radius decreased with age, demonstrating a steepening of the cornea, and confirming previous results. The p value increases with age, indicating a shift toward a more spherical surface. The rate of change in the vertex radius and p value with age are predicted.
随着年龄增长,角膜顶点半径会减小。本研究旨在调查从角膜顶点到周边的变平程度,即表面轮廓,是否也会随年龄变化。
使用EyeSys视频角膜曲率计和拓普康自动角膜曲率计,在一组年轻和年长受试者的水平子午线上测量“p”值(表示从角膜顶点到角膜缘变平速率的参数)和顶点半径。
根据EyeSys数据,通过绘制r2(矢状半径)与y2(距仪器光轴的垂直距离)的图表来计算水平顶点半径和p值。对于拓普康数据,使用先前推导的公式。在拓普康自动角膜曲率计组中,年轻组的平均顶点半径为7.91±0.31,在EyeSys视频角膜曲率计组中为7.98±0.31。在年长组中,拓普康的平均顶点半径为7.68±0.22,EyeSys的平均顶点半径为7.74±0.24。在年轻组中,拓普康的平均p值为0.66±0.09,EyeSys的平均p值为0.78±0.07。在年长组中,拓普康的平均p值为0.74±0.07,EyeSys的平均p值为0.86±0.07。
顶点半径随年龄减小,表明角膜变陡,证实了先前的结果。p值随年龄增加,表明向更球形表面转变。预测了顶点半径和p值随年龄的变化率。