Broome K M, Flynn P M, Simpson D D
Institute of Behavioral Research, Texas Christian University, Fort Worth 76129, USA.
Health Serv Res. 1999 Aug;34(3):791-806.
To examine lifetime and current psychiatric comorbidity measures as predictors of drug abuse treatment retention, and to test the generalizability of results across treatment agencies in diverse settings and with varying practices.
DATA SOURCES/STUDY SETTING: The national Drug Abuse Treatment Outcome Studies (DATOS), a longitudinal study of clients from 96 treatment agencies in 11 U.S. cities.
The design is naturalistic and uses longitudinal analysis of treatment retention in long-term residential, outpatient drug-free, and outpatient methadone treatment modalities; client background (including psychiatric comorbidity) and program service provision are predictors. Clinical thresholds for adequate treatment retention were 90 days for long-term residential and outpatient drug-free, and 360 days for outpatient methadone. Psychiatric indicators included lifetime DSM-III-R diagnoses of depression/anxiety and antisocial personality, and dimensional measures of current symptoms for depression and hostility.
DATA COLLECTION/EXTRACTION METHODS: Data include structured interviews with clients, a survey of treatment program administrators, and program discharge records.
Dimensional measures of current psychiatric symptoms emerged as better predictors than lifetime DSM-III-R diagnoses. In addition, the predictive association of hostility with retention varied significantly across treatment agencies, both in the long-term residential and outpatient drug-free modalities. Other notable findings were that on-site mental health services in long-term residential programs were associated with better retention for clients with symptoms of hostility.
Assessment issues and stability of results across programs are important considerations for treatment research and practice.
研究终生及当前的精神疾病共病指标作为药物滥用治疗留存率预测因素的情况,并检验研究结果在不同环境及不同做法的治疗机构中的普遍性。
数据来源/研究背景:全国药物滥用治疗结果研究(DATOS),一项对来自美国11个城市96家治疗机构的客户进行的纵向研究。
该设计采用自然主义方法,对长期住院、门诊非药物及门诊美沙酮治疗模式下的治疗留存率进行纵向分析;客户背景(包括精神疾病共病情况)及项目服务提供情况为预测因素。长期住院及门诊非药物治疗充足治疗留存率的临床阈值为90天,门诊美沙酮治疗为360天。精神疾病指标包括终生DSM-III-R诊断的抑郁/焦虑及反社会人格,以及当前抑郁和敌意症状的维度测量。
数据收集/提取方法:数据包括对客户的结构化访谈、对治疗项目管理人员的调查以及项目出院记录。
当前精神症状的维度测量比终生DSM-III-R诊断更能作为预测因素。此外,在长期住院及门诊非药物治疗模式中,敌意与留存率之间的预测关联在不同治疗机构间差异显著。其他显著发现是,长期住院项目中的现场心理健康服务与有敌意症状的客户更高的留存率相关。
评估问题及不同项目结果的稳定性是治疗研究和实践的重要考虑因素。