Seemayer N, de Ruiter N, Manojlovic N, Tomingas R
Zentralbl Bakteriol B. 1978 Nov;167(4):296-305.
The cell growth of exponentially growing kidney cell cultures of Cercopithecus aethiops was determined by estimation of protein content. The effect of city smog extracts and its polyaromatic fractions on cell growth was examined. Based on the benzo(a)pyren-content the crude extract of city smog exerted the strongest inhibition of cell growth, followed by non purified and purified fraction of polyaromates. The inhibition of cell growth was dose dependent. Results indicate, that for cell growth inhibition are of importance concentrations of toxic substances and exposition time.
通过蛋白质含量估计来确定埃塞俄比亚猕猴指数生长的肾细胞培养物的细胞生长情况。研究了城市烟雾提取物及其多环芳烃组分对细胞生长的影响。基于苯并(a)芘含量，城市烟雾粗提物对细胞生长的抑制作用最强，其次是多环芳烃的未纯化和纯化组分。细胞生长抑制呈剂量依赖性。结果表明，对于细胞生长抑制而言，有毒物质的浓度和暴露时间很重要。
