Irwin M, Artin K H, Oxman M N
Department of Psychiatry, School of Medicine, University of California at San Diego and the Veterans Affairs Healthcare System, 92161, USA.
Arch Intern Med. 1999;159(15):1701-4. doi: 10.1001/archinte.159.15.1701.
The Center for Epidemiological Studies Depression Scale (CES-D) has been widely used in studies of late-life depression. While the CES-D is convenient to use in most settings, it can present problems for elderly respondents who may find the response format confusing, the questions emotionally stressful, and the time to complete burdensome. A briefer 10-item version has been proposed, but there are few data on its properties as a screening instrument.
The 10-item CES-D was administered in 2 studies. In study 1, a stratified sample of middle-aged depressed patients (n = 40) and comparison controls (n = 43) were administered the CES-D to determine an optimal cutoff score. In study 2, the accuracy of the CES-D optimal cutoff score was tested in a sample of adults older than 60 years (n = 68). Major depression diagnoses were derived from the Structured Clinical Interview for Diagnostic and Statistical Manual of Mental Disorders, Revised Third Edition, with consensus diagnoses using Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition.
Reliability statistics with the 10-item CES-D were found to be comparable to those reported for the original CES-D. Using an optimal cutoff score of 4 in study 1, the sensitivity of the 10-item CES-D was 97%; specificity, 84%; and positive predictive value, 85%. In the study 2 sample of older adults, the sensitivity of the CES-D was 100%; specificity, 93%; and positive predictive value, 38%.
The 10-item CES-D has excellent properties for use as a screening instrument for the identification of major depression in older adults.
流行病学研究中心抑郁量表(CES-D)已广泛应用于老年抑郁症研究。虽然CES-D在大多数情况下使用方便,但对于老年受访者来说可能存在问题,他们可能会觉得回答格式令人困惑、问题在情感上带来压力,且完成所需时间过长。有人提出了一个更简短的10项版本,但关于其作为筛查工具的特性的数据很少。
在两项研究中使用了10项CES-D。在研究1中,对中年抑郁症患者(n = 40)和对照者(n = 43)的分层样本进行了CES-D测试,以确定最佳截断分数。在研究2中,在60岁以上的成年人样本(n = 68)中测试了CES-D最佳截断分数的准确性。重度抑郁症诊断源自《精神障碍诊断与统计手册》修订第三版的结构化临床访谈,并使用《精神障碍诊断与统计手册》第四版进行共识诊断。
发现10项CES-D的可靠性统计数据与原始CES-D报告的数据相当。在研究1中使用最佳截断分数4时,10项CES-D的敏感性为97%;特异性为84%;阳性预测值为85%。在研究2的老年成年人样本中,CES-D的敏感性为100%;特异性为93%;阳性预测值为38%。
10项CES-D作为识别老年人重度抑郁症的筛查工具具有出色的特性。