Alanen A, Laurikainen E
Department of Obstetrics and Gynecology, University of Turku, Finland.
Am J Perinatol. 1999;16(4):181-3. doi: 10.1055/s-2007-993854.
Intra-amniotic infection is often the cause of a second-trimester abortion. The bacterial species involved include bacteria with low pathogenicity like Ureaplasma urealyticum and various Mycoplasma species. In this case we describe an intra-amniotic infection caused by Capnocytophaga sputigena, often found in the normal bacterial flora of the oral cavity, but not in the vagina. Oral sex during pregnancy was the most probable source of the infection. The aborted fetus showed signs of pneumonia upon histologic examination. The bacterial species was identified using broad-spectrum 16S rDNA polymerase chain reaction (PCR) directly from the amniotic fluid and after bacterial culture. Amniotic fluid glucose was below detection level, confirming the presence of an intra-amniotic infection.
羊膜腔内感染常常是孕中期流产的原因。涉及的细菌种类包括致病性较低的细菌，如解脲脲原体和各种支原体。在本病例中，我们描述了由生痰二氧化碳嗜纤维菌引起的羊膜腔内感染，该菌常见于口腔正常菌群中，而非阴道。孕期口交是最可能的感染源。流产胎儿经组织学检查显示有肺炎迹象。通过直接从羊水以及细菌培养后使用广谱16S rDNA聚合酶链反应（PCR）鉴定出了该细菌种类。羊水葡萄糖低于检测水平，证实存在羊膜腔内感染。
