Dunlop Anne L, Mulle Jennifer G, Ferranti Erin P, Edwards Sara, Dunn Alexis B, Corwin Elizabeth J
Emory University School of Nursing, Atlanta, Georgia (Dr Dunlop); Department of Human Genetics, Rollins School of Public Health and School of Medicine, Emory University, Atlanta, Georgia (Dr Mulle); and Nell Hodgson Woodruff School of Nursing, Emory University, Atlanta, Georgia (Dr Ferranti, Ms Edwards, Ms Dunn, and Dr Corwin).
Adv Neonatal Care. 2015 Dec;15(6):377-85. doi: 10.1097/ANC.0000000000000218.
The maternal microbiome is recognized as a key determinant of a range of important maternal and child health outcomes, and together with perinatal factors influences the infant microbiome. This article provides a summary review of research investigating (1) the role of the maternal microbiome in pregnancy outcomes known to adversely influence neonatal and infant health, including preterm birth, cardiometabolic complications of pregnancy such as preeclampsia and gestational diabetes, and excessive gestational weight gain; (2) factors with an established link to adverse pregnancy outcomes that are known to influence the composition of the maternal microbiome; and (3) strategies for promoting a healthy maternal microbiome, recognizing that much more research is needed in this area.
母体微生物群被认为是一系列重要的母婴健康结局的关键决定因素，并且与围产期因素共同影响婴儿微生物群。本文对以下研究进行了综述：（1）母体微生物群在已知对新生儿和婴儿健康有不利影响的妊娠结局中的作用，包括早产、妊娠的心脏代谢并发症如先兆子痫和妊娠期糖尿病，以及孕期体重过度增加；（2）与已知会影响母体微生物群组成的不良妊娠结局有既定联系的因素；（3）促进母体微生物群健康的策略，同时认识到该领域还需要更多的研究。
