Rajamanoharan S, Low N, Jones S B, Pozniak A L
The Caldecot Centre, King's NHS Healthcare Trust, London, UK.
Sex Transm Dis. 1999 Aug;26(7):404-9. doi: 10.1097/00007435-199908000-00008.
Bacterial vaginosis and vaginal douching are both reported to be more common in African-American and Caribbean than white women. It is also thought that douching alters the vaginal milieu. This study was conducted to examine associations between genital cleaning practices, bacterial vaginosis, and ethnic group.
Case-control study of 100 women with bacterial vaginosis, diagnosed by Nugent's criteria, and 100 women without bacterial vaginosis attending a sexually transmitted diseases clinic in an ethnically heterogeneous inner-city area in London, England.
Bacterial vaginosis was more common among black Caribbean than white women (OR, 2.1; 95% CI, 1.1-4.1). Vulval use of bubble bath or antiseptic solutions and douching with proprietary or homemade solutions were significantly more common in women with bacterial vaginosis than without. After controlling for use of vulval and vaginal antiseptics and bubble bath, douching, and a history of bacterial vaginosis, there was no ethnic difference in the occurrence of the condition (adjusted OR, 1.1; 95% CI, 0.5-2.5).
Ethnic differences in genital hygiene behaviors can explain a twofold increase in the risk of bacterial vaginosis in black Caribbean compared with white women. The role of vulval and vaginal cleaning practices in the development of bacterial vaginosis should be examined further in longitudinal or randomized controlled studies.
据报道，细菌性阴道病和阴道灌洗在非裔美国人和加勒比地区女性中比白人女性更为常见。人们还认为灌洗会改变阴道环境。本研究旨在探讨生殖器清洁习惯、细菌性阴道病与种族之间的关联。
对100例经纽金特标准诊断为细菌性阴道病的女性和100例未患细菌性阴道病的女性进行病例对照研究，这些女性均在英国伦敦一个种族多样化的市中心地区的性传播疾病诊所就诊。
加勒比黑人女性患细菌性阴道病的比例高于白人女性（比值比，2.1；95%可信区间，1.1 - 4.1）。细菌性阴道病患者使用外阴泡泡浴或抗菌溶液以及使用专用或自制溶液进行灌洗的情况明显多于未患病者。在控制了外阴和阴道抗菌剂、泡泡浴的使用、灌洗以及细菌性阴道病史后，该病的发生率不存在种族差异（调整后的比值比，1.1；95%可信区间，0.5 - 2.5）。
生殖器卫生行为的种族差异可以解释为什么与白人女性相比，加勒比黑人女性患细菌性阴道病的风险增加了两倍。外阴和阴道清洁习惯在细菌性阴道病发生过程中的作用应在纵向研究或随机对照研究中进一步探讨。
