Bozkurt P, Kaya G, Yeker Y, Tunali Y, Altintaş F
Department of Anesthesiology, Istanbul University Cerrahpaşa Medical Faculty, Istanbul, Turkey.
Anaesthesia. 1999 Sep;54(9):831-4. doi: 10.1046/j.1365-2044.1999.00945.x.
We assessed the cardiorespiratory effects of laparoscopic procedures in 27 infants aged between 36 and 365 days. Infants were monitored and anaesthetised in a standardised manner. Heart rate, mean arterial pressure, end-tidal carbon dioxide and oxygen saturation were recorded, and blood gases were measured at 5 min after intubation, 15 and 30 min after carbon dioxide pneumoperitoneum, 5 min after desufflation and after extubation. The pH, PaO2, base excess, SaO2 and SpO2 decreased, and PCO2 increased by insufflation of carbon dioxide intraperitoneally, and improved following deflation. Changes in pH and PaO2 during the study were statistically significant (p < 0.0001). The increase in PaCO2 30 min after pneumoperitoneum was statistically significant when compared with initial values. Transient arrhythmias were observed in 10 infants 1 min after pneumoperitoneum. There were no statistically significant alterations in heart rate and systolic blood pressure.
我们评估了27名年龄在36至365天之间的婴儿接受腹腔镜手术时的心肺效应。婴儿以标准化方式进行监测和麻醉。记录心率、平均动脉压、呼气末二氧化碳和血氧饱和度，并在插管后5分钟、二氧化碳气腹后15和30分钟、放气后5分钟以及拔管后测量血气。经腹腔注入二氧化碳后，pH值、动脉血氧分压（PaO2）、碱剩余、血氧饱和度（SaO2）和脉搏血氧饱和度（SpO2）下降，而二氧化碳分压（PCO2）升高，放气后情况改善。研究期间pH值和PaO2的变化具有统计学意义（p < 0.0001）。气腹后30分钟时PaCO2的升高与初始值相比具有统计学意义。气腹后1分钟，10名婴儿出现短暂性心律失常。心率和收缩压无统计学意义的改变。
