Süleyman H, Demirezer L O, Kuruüzüm A, Banoğlu Z N, Göçer F, Ozbakir G, Gepdiremen A
Department of Pharmacology, Faculty of Medicine, Atatürk University, Erzurum, Turkey.
J Ethnopharmacol. 1999 May;65(2):141-8. doi: 10.1016/s0378-8741(98)00175-5.
Pharmacological studies were conducted with the aqueous extract of roots of Rumex patientia L. (Polygonaceae) on experimental animals. For evaluating the antiinflammatory activity, carrageenan, histamine, dextrane, serotonine formaldehyde-induced oedema tests, cotton-pellet granuloma, and Kabak tests in rats were used. The extract was found to possess antiinflammatory activity. Acute toxicity studies revealed that the extract up to a dose of 3 mg/kg orally was nontoxic.
对皱叶酸模(蓼科)根的水提取物在实验动物身上进行了药理学研究。为评估其抗炎活性,采用了角叉菜胶、组胺、右旋糖酐、血清素甲醛诱导的水肿试验、棉球肉芽肿试验以及大鼠的卡巴克试验。结果发现该提取物具有抗炎活性。急性毒性研究表明,口服剂量高达3mg/kg的提取物无毒。