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皱叶酸模根水提取物的抗炎作用

Antiinflammatory effect of the aqueous extract from Rumex patientia L. roots.

作者信息

Süleyman H, Demirezer L O, Kuruüzüm A, Banoğlu Z N, Göçer F, Ozbakir G, Gepdiremen A

机构信息

Department of Pharmacology, Faculty of Medicine, Atatürk University, Erzurum, Turkey.

出版信息

J Ethnopharmacol. 1999 May;65(2):141-8. doi: 10.1016/s0378-8741(98)00175-5.

DOI:10.1016/s0378-8741(98)00175-5
PMID:10465654
Abstract

Pharmacological studies were conducted with the aqueous extract of roots of Rumex patientia L. (Polygonaceae) on experimental animals. For evaluating the antiinflammatory activity, carrageenan, histamine, dextrane, serotonine formaldehyde-induced oedema tests, cotton-pellet granuloma, and Kabak tests in rats were used. The extract was found to possess antiinflammatory activity. Acute toxicity studies revealed that the extract up to a dose of 3 mg/kg orally was nontoxic.

摘要

对皱叶酸模(蓼科)根的水提取物在实验动物身上进行了药理学研究。为评估其抗炎活性,采用了角叉菜胶、组胺、右旋糖酐、血清素甲醛诱导的水肿试验、棉球肉芽肿试验以及大鼠的卡巴克试验。结果发现该提取物具有抗炎活性。急性毒性研究表明,口服剂量高达3mg/kg的提取物无毒。

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