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与吲哚美辛相比,皱叶酸模水提取物对二甲苯和透明质酸酶诱导的毛细血管通透性的影响。

Effect of the aqueous extract of Rumex patientia on xylol and hyaluronidase induced capillary permeability compared to indomethacin.

作者信息

Süleyman H, Demirezer L O, Kuruüzüm A, Büyükokuroğlu M E, Gŏçer F, Banoğlu Z N, Gepdiremen A

机构信息

Department of Pharmacology, Faculty of Medicine, Atatürk University, Erzurum, Turkey.

出版信息

Pharmazie. 2001 Jan;56(1):92-3.

Abstract

In this study, the effect of an aqueous extract of Rumex patientia L. (Polygonaceae) (D-1) on capillary permeability which was induced by xylol and hyaluronidase was investigated. Experiments were conducted on rabbits according to Monakova and Matusis methods. The effects of D-1 were compared to those of indomethacin, which was used as a control throughout the experiment. Both D-1 (100 mg/kg) and indomethacin (10 mg/kg) were administered orally. As a result, D-1 inhibited capillary permeability, which was induced by xylol and hyaluronidase, and it was found that it was as effective as indomethacin.

摘要

在本研究中,对皱叶酸模(蓼科)水提取物(D - 1)对由二甲苯和透明质酸酶诱导的毛细血管通透性的影响进行了研究。根据莫纳科娃和马图西斯方法在兔子身上进行实验。将D - 1的效果与吲哚美辛的效果进行比较,吲哚美辛在整个实验中用作对照。D - 1(100毫克/千克)和吲哚美辛(10毫克/千克)均口服给药。结果,D - 1抑制了由二甲苯和透明质酸酶诱导的毛细血管通透性,并且发现其效果与吲哚美辛相同。

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