Ogen-Odoi A, Miller B R, Happ C M, Maupin G O, Burkot T R
Ugandan Virus Research Institute, Entebbe.
Am J Trop Med Hyg. 1999 Mar;60(3):439-40. doi: 10.4269/ajtmh.1999.60.439.
Small wild vertebrates were trapped during an investigation into possible vertebrate reservoirs of o'nyong-nyong (ONN) fever virus in Uganda in 1997. Antibody neutralization test results and virus isolation attempts were negative for ONN virus, confirming the work of earlier investigators, who also failed to find evidence for a nonhuman ONN virus reservoir. In the course of these ONN virus studies, Thogoto virus was isolated from one of eight banded mongooses (Mongos mungo). This is the first isolation of Thogoto virus from a wild vertebrate. Neutralizing antibodies to Thogoto virus were also found in two of the other mongooses.
1997年在乌干达对奥尼昂尼昂(ONN)热病毒可能的脊椎动物宿主进行调查期间,捕获了小型野生脊椎动物。ONN病毒的抗体中和试验结果及病毒分离尝试均为阴性,证实了早期研究人员的工作,他们也未能找到非人类ONN病毒宿主的证据。在这些ONN病毒研究过程中,从八只条纹獴(Mongos mungo)中的一只分离出了托戈托病毒。这是首次从野生脊椎动物中分离出托戈托病毒。在另外两只獴中也发现了针对托戈托病毒的中和抗体。