Guillem F, Rougier A, Claverie B
Laboratory of Human Neruocognitive Sciences, Douglas Hospital Research Lab. of Human Neurocognitive Sciences, Douglas Hospital research Centre - Clinical Unit (FBC1), Verdun, Quebec, Canada.
J Cogn Neurosci. 1999 Jul;11(4):437-58. doi: 10.1162/089892999563526.
Prior exposure to a stimulus can facilitate the performance to subsequent presentations of that stimulus. ERP studies have shown that this facilitation is associated with the modulation of two components (N400 and P600). Investigation of the time course of both behavioral and ERP repetition effects have led to the assumption that it is subserved by the combination of at least two mechanisms operating at different time-points: a short-delay semantic activation and a long-lasting episodic mechanism. The present experiment recorded intracranial ERPs from various structures during a continuous recognition memory task to investigate the respective contribution of the different brain regions to short- and long-delay ERP repetition effects. The results are in good agreement with both the classical neuropsychological literature and the more recent data obtained with functional imagery techniques. They provide electrophysiological evidence of multiple anatomo-functional memory systems in the human brain: a short-term semantic activation system and a long-term episodic memory system, with interface structures that coordinate the functioning of these two systems.
先前对某一刺激的接触能够促进对该刺激后续呈现的表现。ERP研究表明，这种促进作用与两个成分（N400和P600）的调制有关。对行为和ERP重复效应的时间进程的研究导致了这样一种假设，即它是由至少两种在不同时间点起作用的机制的组合所支持的：一种是短延迟语义激活，另一种是持久的情景机制。本实验在连续识别记忆任务期间记录了来自各种结构的颅内ERP，以研究不同脑区对短延迟和长延迟ERP重复效应的各自贡献。结果与经典神经心理学文献以及使用功能成像技术获得的最新数据都非常吻合。它们提供了人类大脑中多个解剖功能记忆系统的电生理证据：一个短期语义激活系统和一个长期情景记忆系统，以及协调这两个系统功能的接口结构。
