Adams C W, Bullimore M A, Wall M, Fingeret M, Johnson C A
School of Optometry, University of California, Berkeley, USA.
Optom Vis Sci. 1999 Aug;76(8):582-7. doi: 10.1097/00006324-199908000-00027.
To determine the influence of normal aging on contrast sensitivity for frequency doubling technology (FDT) perimetry.
Contrast sensitivity measures were obtained for frequency-doubled stimuli (0.25 cycles per degree sinusoidal gratings undergoing 25 Hz counterphase flicker) at 17 target locations (4 per quadrant plus the central 5 degrees ) using a prototype of the Welch Allyn (Skaneateles, NY)/Humphrey Systems FDT perimeter (Humphrey Systems, Dublin, CA). A total of 407 normal subjects (761 eyes) between the ages of 15 and 85 years were tested.
Between the ages of 15 and 60 years there was an approximately linear decrease in contrast sensitivity of 0.6 dB per decade. After the age of 70, there was a slightly greater sensitivity loss with age. There were no meaningful differences in sensitivity loss as a function of age for different visual field locations. A small but consistent reduction in contrast sensitivity (approximately 0.7 dB) was found at all visual field locations for the second eye tested that may be due to a central adaptation process.
Normal aging effects for FDT perimetry are similar to those obtained for conventional automated perimetry, except that the FDT perimetry aging effects do not appear to be eccentricity dependent. These normative data provide a basis for establishing a statistical analysis procedure and probability plots for FDT perimetry.
确定正常衰老对频率加倍技术（FDT）视野检查对比度敏感度的影响。
使用Welch Allyn（纽约州斯卡奈特勒斯）/Humphrey Systems FDT视野计（加利福尼亚州都柏林的Humphrey Systems）原型，在17个目标位置（每个象限4个加上中央5度）测量频率加倍刺激（每度0.25周正弦光栅，以25赫兹反相闪烁）的对比度敏感度。共测试了407名年龄在15至85岁之间的正常受试者（761只眼）。
15至60岁之间，对比度敏感度大约每十年线性下降0.6分贝。70岁以后，随着年龄增长敏感度损失稍大。不同视野位置的敏感度损失随年龄变化无显著差异。在测试的第二只眼中，所有视野位置的对比度敏感度均有小幅但持续的下降（约0.7分贝），这可能是由于中枢适应过程所致。
FDT视野检查的正常衰老效应与传统自动视野检查相似，只是FDT视野检查的衰老效应似乎与偏心度无关。这些标准数据为建立FDT视野检查的统计分析程序和概率图提供了依据。
