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[头颈部癌症患者牙科良好实践的标准、选项和建议(SOR)。法国癌症中心联合会(FNCLCC)]

[Standards, Options and Recommendations (SOR) for good practices in dentistry for head and neck cancer patients. Federation of the French Cancer Centres (FNCLCC)].

作者信息

Maire F, Borowski B, Collangettes D, Farsi F, Guichard M, Gourmet R, Kreher P

机构信息

Centre Alexis-Vautrin, Nancy.

出版信息

Bull Cancer. 1999 Jul-Aug;86(7-8):640-65.

Abstract

CONTEXT

The Standards, Options and Recommendations (SOR), initiated in 1993, is a collaborative project between the Federation of the French Cancer Centres (FNCLCC), the 20 French Cancer Centres and specialists from French Public Universities, General Hospitals and Private Clinics. The main objective is the development of clinical practice guidelines to improve the quality of health care and outcomes for cancer patients. The methodology is based on literature review and critical appraisal by a multidisciplinary experts group, with feedback from specialists in cancer care delivery.

OBJECTIVES

To develop clinical practice guidelines for dentistry and oral hygiene in head and neck cancer patients.

METHODS

Data have been identified by literature search using Medline (up to January 1999) and personal reference lists. The main end points considered were risk factors for treatment related late effects, safety and quality of life, efficacy of dental preventative measures and treatment. Once the guidelines were defined, the document was submitted to reviewers for peer review and to the medical committees of the 20 French Cancer Centres for review and agreement.

RESULTS

The key recommendations are: 1) before receiving radiotherapy, surgery and chemotherapy for head and neck cancer, patients must benefit from a multidisciplinary approach including dental evaluation; 2) the patients must be informed of precautions and educated about oral hygiene; 3) after radiotherapy, the most important dental late effect to prevent is radionecrosis, in accordance with the oral and dental state, the dentist may propose conservation or extraction of teeth, fluoridation and regular follow-up; 4) during chemotherapy, the principal complications are mucositis, haemorrhage and infection risk; 5) after surgery, the dentist may propose prosthetic measures with the aim functional, aesthetic and psychological benefit; 6) in the particular case of children, treatment and prevention are the same as for adults but the follow-up is specific because of the dental development.

摘要

背景

1993年发起的《标准、选项与建议》(SOR)是法国癌症中心联合会(FNCLCC)、20家法国癌症中心以及法国公立大学、综合医院和私立诊所的专家之间的合作项目。主要目标是制定临床实践指南,以提高癌症患者的医疗质量和治疗效果。该方法基于多学科专家组的文献综述和批判性评估,并听取癌症护理专家的反馈意见。

目的

制定头颈部癌症患者牙科和口腔卫生的临床实践指南。

方法

通过使用Medline(截至1999年1月)进行文献检索以及个人参考文献列表来确定数据。所考虑的主要终点是治疗相关迟发效应的危险因素、安全性和生活质量、牙科预防措施和治疗的疗效。一旦确定了指南,该文件便提交给审阅者进行同行评审,并提交给20家法国癌症中心的医学委员会进行审查和批准。

结果

关键建议如下:1)在接受头颈部癌症的放疗、手术和化疗之前,患者必须受益于包括牙科评估在内的多学科方法;2)必须告知患者注意事项并对其进行口腔卫生教育;3)放疗后,要预防的最重要的牙科迟发效应是放射性骨坏死,根据口腔和牙齿状况,牙医可建议保留或拔除牙齿、进行氟化处理并定期随访;4)化疗期间,主要并发症是粘膜炎、出血和感染风险;5)手术后,牙医可建议采取修复措施,以获得功能、美观和心理方面的益处;6)在儿童的特殊情况下,治疗和预防与成人相同,但由于牙齿发育情况,随访具有特殊性。

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