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使用磷酸钙骨水泥进行骨重建:一项批判性综述。

Reconstruction of bone using calcium phosphate bone cements: a critical review.

作者信息

Schmitz J P, Hollinger J O, Milam S B

机构信息

Department of Oral and Maxillo-Facial Surgery, The University of Texas Health Science Center at San Antonio 78284-7823, USA.

出版信息

J Oral Maxillofac Surg. 1999 Sep;57(9):1122-6. doi: 10.1016/s0278-2391(99)90338-5.

DOI:10.1016/s0278-2391(99)90338-5
PMID:10484115
Abstract

The calcium phosphate cements (CPCs) are rapidly emerging as a new technology in craniofacial surgery and will soon impact many areas of orthopedic and maxillofacial reconstructive surgery as well. These materials are, in many ways, substantially different from the previously marketed dense, crystalline, hydroxyapatite (HA) ceramic materials of the 1980s. The CPCs are blends of amorphous and crystalline calcium phosphate compounds and set to produce HA. These materials 1) have x-ray diffraction spectra similar to the mineral phase of bone, 2) set endothermically at body temperature, 3) are capable of being injected into fractures or bone defects, 4) have compressive strengths equal to or greater than bone, 5) form chemical bonds to the host bone, and 6) may exhibit osteoconductive properties. This review provides an overall commentary on the different types of CPCs, emphasizing those materials currently on the market or soon to emerge in the marketplace.

摘要

磷酸钙骨水泥(CPCs)正迅速成为颅面外科的一项新技术,并且很快也将对骨科和颌面重建外科的许多领域产生影响。在很多方面,这些材料与20世纪80年代以前上市的致密、结晶性羟基磷灰石(HA)陶瓷材料有很大不同。CPCs是无定形和结晶性磷酸钙化合物的混合物,并会固化生成HA。这些材料1)具有与骨矿物质相类似的X射线衍射光谱,2)在体温下吸热固化,3)能够注入骨折部位或骨缺损处,4)抗压强度等于或大于骨,5)与宿主骨形成化学键,6)可能具有骨传导特性。本综述对不同类型的CPCs进行了全面评述,重点介绍了目前市场上已有的或即将上市的材料。

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