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磷限制期间磷壁酸合成的调控

Control of teichoic acid synthesis during phosphate limitation.

作者信息

Glaser L, Loewy A

出版信息

J Bacteriol. 1979 Jan;137(1):327-31. doi: 10.1128/jb.137.1.327-331.1979.

DOI:10.1128/jb.137.1.327-331.1979
PMID:104964
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC218454/
Abstract

The synthesis of teichoic acids was examined in Bacillus subtilis Marburg grown under conditions of phosphate limitation. The results indicate that the inhibition of polyglycerolphosphate synthesis observed under these conditions is the result of two processes. The first process is reversible and is independent of new protein synthesis; the second process is irreversible and requires the synthesis of new protein. During growth, under conditions of phosphate limitation, there is a slow decrease in the level of CDP glycerol pyrophosphorylase activity which is by itself not sufficient to account for the decrease in the rate of polyglycerolphosphate synthesis.

摘要

在磷酸盐限制条件下生长的枯草芽孢杆菌马伯格菌株中,对磷壁酸的合成进行了研究。结果表明,在这些条件下观察到的聚甘油磷酸合成的抑制是两个过程的结果。第一个过程是可逆的,且与新蛋白质合成无关;第二个过程是不可逆的,需要新蛋白质的合成。在生长过程中,在磷酸盐限制条件下,CDP甘油焦磷酸化酶活性水平缓慢下降,但其本身不足以解释聚甘油磷酸合成速率的下降。

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Control of teichoic acid synthesis during phosphate limitation.磷限制期间磷壁酸合成的调控
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2
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引用本文的文献

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Teichoic and teichuronic acids: biosynthesis, assembly, and location.磷壁酸和磷壁醛酸:生物合成、组装及定位
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Biosynthesis of D-alanyl-lipoteichoic acid in Lactobacillus casei: D-alanyl-lipophilic compounds as intermediates.干酪乳杆菌中D-丙氨酰-脂磷壁酸的生物合成:以D-丙氨酰亲脂性化合物为中间体
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Cell wall metabolism in Bacillus subtilis subsp. niger: effects of changes in phosphate supply to the culture.枯草芽孢杆菌黑色亚种中的细胞壁代谢:培养物中磷供应变化的影响
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本文引用的文献

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Protein measurement with the Folin phenol reagent.使用福林酚试剂进行蛋白质测定。
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THE SYNTHESIS OF TEICHOIC ACID. IV. ON THE REGULATION OF CYTIDINE 5'-DIPHOSPHATEGLYCEROL CONCENTRATION.磷壁酸的合成。IV. 关于5'-二磷酸胞苷甘油浓度的调节
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On the mode of in vivo assembly of the cell wall of Bacillus subtilis.关于枯草芽孢杆菌细胞壁的体内组装模式。
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8
Periplasmic nucleoside diphosphate sugar hydrolase from Bacillus subtilis.来自枯草芽孢杆菌的周质核苷二磷酸糖水解酶。
Biochemistry. 1970 Mar 3;9(5):1140-7. doi: 10.1021/bi00807a014.
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The effect of carbon and nitrogen sources on the level of metabolic intermediates in Escherichia coli.碳源和氮源对大肠杆菌中代谢中间体水平的影响。
J Biol Chem. 1971 Nov;246(21):6511-21.
10
Control of teichoic and teichuronic acid biosynthesis in Bacillus subtilis 168trp. Evidence for repression of enzyme synthesis and inhibition of enzyme activity.枯草芽孢杆菌168trp中磷壁酸和磷壁醛酸生物合成的调控。酶合成受抑制及酶活性受抑制的证据。
Biochim Biophys Acta. 1976 Apr 23;428(2):516-24. doi: 10.1016/0304-4165(76)90060-x.