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磷酸盐限制期间磷壁酸合成的调控

Regulation of teichoic acid synthesis during phosphate limitation.

作者信息

Glaser L, Loewy A

出版信息

J Biol Chem. 1979 Apr 10;254(7):2184-6.

PMID:107156
Abstract

Bacillus subtilis W-23, when placed in phosphate-free medium, ceases to synthesize teichoic acid and synthesizes teichuronic acid. The enzymatic basis for the cessation of teichoic acid synthesis is the irreversible inhibition of the first membrane-bound enzyme involved in teichoic acid synthesis which catalyzes the reaction Undecapenol-P + UDP-GlcNAc leads to undecaprenol-P-P-GlcNAc + UMP.

摘要

枯草芽孢杆菌W-23置于无磷酸盐培养基中时,会停止合成磷壁酸并转而合成磷酰壁酸。磷壁酸合成停止的酶学基础是参与磷壁酸合成的第一种膜结合酶被不可逆抑制,该酶催化反应:十一异戊烯醇磷酸 + UDP-葡萄糖胺生成十一异戊烯醇二磷酸葡萄糖胺 + 尿苷一磷酸。

相似文献

1
Regulation of teichoic acid synthesis during phosphate limitation.磷酸盐限制期间磷壁酸合成的调控
J Biol Chem. 1979 Apr 10;254(7):2184-6.
2
Control of teichoic and teichuronic acid biosynthesis in Bacillus subtilis 168trp. Evidence for repression of enzyme synthesis and inhibition of enzyme activity.枯草芽孢杆菌168trp中磷壁酸和磷壁醛酸生物合成的调控。酶合成受抑制及酶活性受抑制的证据。
Biochim Biophys Acta. 1976 Apr 23;428(2):516-24. doi: 10.1016/0304-4165(76)90060-x.
3
Influence of phosphate supply on teichoic acid and teichuronic acid content of Bacillus subtilis cell walls.磷酸盐供应对枯草芽孢杆菌细胞壁磷壁酸和磷壁醛酸含量的影响。
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Control of teichoic acid synthesis during phosphate limitation.磷限制期间磷壁酸合成的调控
J Bacteriol. 1979 Jan;137(1):327-31. doi: 10.1128/jb.137.1.327-331.1979.
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Activation and inactivation of synthesis of secondary wall polymers in Bacillus subtilis W23.枯草芽孢杆菌W23中次生壁聚合物合成的激活与失活
Arch Microbiol. 1983 Jun;134(3):222-6. doi: 10.1007/BF00407762.
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Biosynthesis of linkage units for teichoic acids in gram-positive bacteria: distribution of related enzymes and their specificities for UDP-sugars and lipid-linked intermediates.革兰氏阳性菌中磷壁酸连接单元的生物合成:相关酶的分布及其对尿苷二磷酸糖和脂质连接中间体的特异性
J Bacteriol. 1989 Feb;171(2):940-6. doi: 10.1128/jb.171.2.940-946.1989.
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Control of synthesis of wall teichoic acid during balanced growth of Bacillus subtilis W23.
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The regulation of synthesis of wall polymers and of wall assembly in Bacillus.芽孢杆菌中细胞壁聚合物合成及细胞壁组装的调控
Biochem Soc Trans. 1985 Dec;13(6):994-6. doi: 10.1042/bst0130994.
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Control of teichoic acid synthesis in Bacillus licheniformis ATCC 9945.地衣芽孢杆菌ATCC 9945中磷壁酸合成的调控
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Biosynthesis of wall teichoic acids in Staphylococcus aureus H, Micrococcus varians and Bacillus subtilis W23. Involvement of lipid intermediates containing the disaccharide N-acetylmannosaminyl N-acetylglucosamine.金黄色葡萄球菌H、变异微球菌和枯草芽孢杆菌W23中壁磷壁酸的生物合成。含二糖N-乙酰甘露糖胺基N-乙酰葡糖胺的脂质中间体的参与。
Eur J Biochem. 1985 Dec 16;153(3):639-45. doi: 10.1111/j.1432-1033.1985.tb09348.x.

引用本文的文献

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Microbiol Mol Biol Rev. 1999 Mar;63(1):174-229. doi: 10.1128/MMBR.63.1.174-229.1999.
2
Teichoic and teichuronic acids: biosynthesis, assembly, and location.磷壁酸和磷壁醛酸:生物合成、组装及定位
Microbiol Rev. 1981 Jun;45(2):211-43. doi: 10.1128/mr.45.2.211-243.1981.
3
Influence of phosphate supply on teichoic acid and teichuronic acid content of Bacillus subtilis cell walls.
磷酸盐供应对枯草芽孢杆菌细胞壁磷壁酸和磷壁醛酸含量的影响。
J Bacteriol. 1982 Jul;151(1):367-75. doi: 10.1128/jb.151.1.367-375.1982.
4
Biosynthesis of D-alanyl-lipoteichoic acid in Lactobacillus casei: D-alanyl-lipophilic compounds as intermediates.干酪乳杆菌中D-丙氨酰-脂磷壁酸的生物合成:以D-丙氨酰亲脂性化合物为中间体
J Bacteriol. 1981 Apr;146(1):239-50. doi: 10.1128/jb.146.1.239-250.1981.
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Effects of carbon source and growth rate on cell wall composition of Bacillus subtilis subsp. niger.碳源和生长速率对枯草芽孢杆菌黑色亚种细胞壁组成的影响。
J Bacteriol. 1980 Oct;144(1):238-46. doi: 10.1128/jb.144.1.238-246.1980.
6
Activation and inactivation of synthesis of secondary wall polymers in Bacillus subtilis W23.枯草芽孢杆菌W23中次生壁聚合物合成的激活与失活
Arch Microbiol. 1983 Jun;134(3):222-6. doi: 10.1007/BF00407762.
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Cell wall metabolism in Bacillus subtilis subsp. niger: effects of changes in phosphate supply to the culture.枯草芽孢杆菌黑色亚种中的细胞壁代谢:培养物中磷供应变化的影响
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J Bacteriol. 1991 Jul;173(14):4341-6. doi: 10.1128/jb.173.14.4341-4346.1991.