Crouse U, Laine-Alava M T
Department of Physiology, University of Kentucky, Lexington 40536-0084, USA.
Laryngoscope. 1999 Sep;109(9):1503-8. doi: 10.1097/00005537-199909000-00027.
The purpose of this study was to evaluate the variation of airflow rate and oral-nasal pressure with age, body mass index (BMI), and gender (i.e., to evaluate whether the effects of age, BMI, and gender on airflow rate and pressures are convergent with their effects on nasal cross-sectional area and resistance).
A cross-sectional study of 332 subjects (214 female and 118 male subjects) aged 16 to 82 years.
The aerodynamic measurements of nasal airflow rate and nasal and oral pressures were performed by posterior rhinomanometry. Age, gender, weight, and height were recorded for each subject, and the BMI was calculated. The effects of age, BMI, and gender on airflow rate and nasal and oral pressures were estimated by ANOVA.
Nasal airflow rate and oral and nasal pressures increased with increasing BMI. In addition, the mean values of airflow rate and pressures were significantly higher in male than in female subjects. Increasing age was related to increased oral pressure, but was not associated with airflow rate or nasal pressure.
This study suggests that, on the contrary to the findings in children and adolescents, BMI and gender should be taken into consideration when measuring the patency of upper airway in adults.
本研究旨在评估气流速率和口鼻压力随年龄、体重指数(BMI)及性别的变化情况(即评估年龄、BMI和性别对气流速率及压力的影响是否与其对鼻横截面积和阻力的影响一致)。
对332名年龄在16至82岁之间的受试者(214名女性和118名男性)进行横断面研究。
采用后鼻测压法对鼻气流速率以及鼻压和口腔压力进行空气动力学测量。记录每位受试者的年龄、性别、体重和身高,并计算BMI。通过方差分析评估年龄、BMI和性别对气流速率以及鼻压和口腔压力的影响。
鼻气流速率以及鼻压和口腔压力随BMI的增加而升高。此外,男性受试者的气流速率和压力平均值显著高于女性受试者。年龄增长与口腔压力升高有关,但与气流速率或鼻压无关。
本研究表明,与儿童和青少年的研究结果相反,在测量成人上呼吸道通畅性时应考虑BMI和性别因素。